Disease Modification
Osteoarthritis (OA) is a significant and growing concern to a large segment of the population. Effective treatments for slowing or stopping the progression of the disease are not available despite…
Surgery for Osteoarthritis of the Knee
Although total knee replacement is an excellent treatment of end-stage osteoarthritis of the knee in the older (>65 years) population, many patients with less severe disease are significantly impacted by…
Update on the Role of Muscle in the Genesis and Management of Knee Osteoarthritis
This updated review outlines the influence of muscle activity on knee joint loading, describes the deficits in muscle function observed in people with knee osteoarthritis, and summarizes available evidence pertaining…
Chronic Disease Management
Osteoarthritis is the most prevalent chronic joint disease worldwide. The incidence and prevalence are increasing as the population ages and lifestyle risk factors such as obesity increase. There are several…
The Health and Structural Consequences of Acute Knee Injuries Involving Rupture of the Anterior Cruciate Ligament
Although there is an abundance of literature regarding the development of knee osteoarthritis after rupture of the anterior cruciate ligament (ACL), the mechanism underlying this link is not clear. Recent…
Imaging of Osteoarthritis
Osteoarthritis (OA) is the most prevalent joint disorder in the elderly, and there is no effective treatment. Imaging is essential for evaluating the synovial joint structures (including cartilage, meniscus, subchondral…
Diagnosis and Clinical Presentation of Osteoarthritis
Osteoarthritis (OA), the commonest arthropathy, targets the knees, hips, finger interphalangeal joints, thumb bases, first metatarsophalangeal joints, and spinal facet joints, and displays marked heterogeneity of clinical presentation. Signs of…
The Measurement of Joint Mechanics and Their Role in Osteoarthritis Genesis and Progression
Mechanics play a role in the initiation and progression of osteoarthritis. However, our understanding of which mechanical parameters are most important, and what their impact is on the disease, is…
Epidemiology of Osteoarthritis
Osteoarthritis (OA) is the most common form of arthritis in the United States and is a leading cause of disability. It is typically defined in epidemiologic studies by radiographic findings…
Lipid-Associated Rheumatologic Syndromes
Rheumatologic manifestations of hyperlipidemia and lipid-associated arthritis are rarely seen in the rheumatologist’s office. On the other hand, a rheumatologist may be the clinician who identifies and initiates proper therapy…
