Rotator Cuff Augmentation
Abstract Massive rotator cuff tears are often chronic in presentation and present with many factors that may inhibit successful repair. Retear rate of large-to-massive rotator cuff tears approaches 70% in…
Preserving the Articulating Surface of the Knee
Abstract Numerous surgical interventions have been developed and refined over the last few decades in an attempt to preserve the articular surface of the knee. Conservative options have more recently…
Biologics in Orthopaedic Surgery
Abstract A cell is the most fundamental unit of a living organism. For the most part, a cell is a small membrane-enclosed structure that consists of an aqueous solution of…
Biologics in Orthopedic Surgery: Ligament Reconstruction in the Knee
Abstract The ligaments of the knee function as static stabilizers of a dynamic joint. The anterior cruciate ligament (ACL) is commonly injured during sports; subsequently, ACL reconstruction is one of…
Orthobiologics in Osteoarthritis
Abstract Osteoarthritis has emerged as one of the major public health problems with a burden of disease that significantly affects the world’s aging population. Osteoarthritis is a progressive degeneration of…
Biologics in Sports Medicine—Introduction
Abstract The use of biologics in sports medicine has increased over the years, as the available research shows their potential to increase healing rates and improve outcomes. This chapter presents…
Allograft Tissue Safety and Technology
Abstract Allograft tissues are commonly used by orthopedic surgeons and are processed using a variety of technologies to increase safety and clinical use. For safety, although disease transmission is a…
Growth Factors
Abstract The use of growth factors and platelet-rich plasma (PRP) in orthopedic surgery is a rapidly expanding area of research with a wide array of possible clinical applications. PRP and…
FDA Regulations and Their Impact
Abstract Progress of biologics in orthopaedic surgery faces a delicate balance of clinical application and technology development in the face of government regulations. While early development of orthobiologics was in…
The Role of Orthobiologics in Orthopaedics
Abstract: Orthobiologics have emerged as a new class of substances that allow for novel ways of treating many orthopedic diseases by harnessing or mimicking natural growth factors found within the…
