10.1055/b-0035-121623 1.4 General assessment and management of the polytrauma patient Wolfgang K Ertel, James F Kellam 1 Introduction Polytrauma is defined as a syndrome of multiple injuries that exceeds an…
10.1055/b-0035-122008 8 Whole Bone Biomechanics Grace Kim and Marjolein C. H. van der Meulen A primary function of the skeleton is to bear loads, supporting the body and allowing for…
10.1055/b-0035-122039 39 Molecular Testing Esther M.M. Van Lieshout Measuring expression of specific proteins can be valuable when assessing local reactions at fracture sites or when assessing progression of healing. Proteins…
10.1055/b-0035-122036 36 Cartilage Explants and Organ Culture Models Innes D.M. Smith Cartilage is a unique tissue that allows the frictionless motion of a joint while withstanding considerable forces. Unfortunately, for…
10.1055/b-0035-122045 45 In Vivo Models for Articular Cartilage Repair Paul Hindle The translation of basic science research requires rigorous investigation prior to human clinical trials. An important step in this…
10.1055/b-0035-122043 43 Models for Impaired Healing Joseph Borrelli, Jr. Fracture healing occurs by one of two well-described ways. Direct fracture healing, which is believed to be uncommon in nature, involves…
10.1055/b-0035-122022 22 Computational Biomechanics of Bone Pankaj Pankaj “Computational” mechanics comprises simulating the mechanical response of an object, such as bone, using models created on a computer. The mechanics is…
10.1055/b-0035-122046 46 In Vivo Soft Tissue Models Melanie Jean Coathup, Catherine Jane Pendegrass, Allen Edward Goodship, and Gordon William Blunn This chapter describes the use of a plethora of different…
10.1055/b-0035-122044 44 In Vivo Models for Bone and Joint Infections Volker Alt, Christoph Henkenberens, and Reinhard Schnettler Bone and joint infections do not represent a uniform disease, but a heterogeneous…
10.1055/b-0035-122040 40 Genetically Modified Models for Bone Repair Rana Abou-Khalil and Céline Colnot Delayed fracture repair and nonunions represent a major clinical challenge due to the lack of understanding of…
