Etiopathogenesis of Osteoarthritis A. Robin Poole Farshid Guilak Steven B. Abramson Osteoarthritis (OA) is a condition that represents a pathological imbalance of degradative and reparative processes involving the whole joint…
Features of Osteoarthritis at Specific Sites Features of osteoarthritis of the knee The knee is comprised of one synovial cavity with three principle compartments: the medial and lateral tibiofemoral joints,…
Epidemiology of Osteoarthritis Leena Sharma Dipali Kapoor Introduction Osteoarthritis (OA) is the most common form of arthritis and a leading cause of chronic disability, in large part due to knee…
Subsets of Osteoarthritis Generalized osteoarthritis Early epidemiological studies using radiological surveys detailed the fact that many patients had osteoarthritis of multiple joints, suggesting a generalized, in-built predisposition (3.1). Furthermore, the…
Principles of Management Introduction In the management of osteoarthritis, there are several tools available (5.1). There are a wide number of options, including non-pharmacological, pharmacological, and surgical options, which may…
Introduction What is osteoarthritis? The answer to this apparently simple question is an ongoing problem for a condition that is so common. Everyone seems to be able to recognize ‘osteoarthritis’…
General Features of Osteoarthritis What are the clinical features of osteoarthritis? The clinical features of osteoarthritis relate to both symptoms and signs. As has been discussed in Chapter 1, the…
Management of Osteoporosis Introduction Bone loss with ageing is universal and many will become osteoporotic in later life with increased risk of fracture. Measures therefore need to be taken by…
Future Therapeutic Options Paul D. Miller Current osteoporosis therapies have been shown to reduce the risk of fragility fractures generally from 50% to 65% over a period of 3 years….
Clinical Cases Pauline M. Camacho Paul D. Miller Case 1 History A 61-year-old white woman had a dual-energy x-ray absorptiometry (DXA) scan ordered by her primary-care physician. Other than mild…
