Noninvasive Biochemical Markers in Osteoarthritis Patrick Garnero Introduction Osteoarthritis (OA) is a highly prevalent age-related disease characterized by an abnormal and degraded cartilage, associated with synovitis and variable subchondral bone…
Magnetic Resonance Imaging Charles G. Peterfy Julie C. DiCarlo Manish Kothari Imaging Osteoarthritis with Magnetic Resonance Imaging For more than two decades, magnetic resonance imaging (MRI) has been the imaging…
Laboratory Findings in Osteoarthritis Roy D. Altman As a clinical entity, osteoarthritis (OA) is a constellation of clinical, radiographic, and synovial fluid findings. To date there are no pathognomonic laboratory…
Ultrasound and Alternative Imaging Outcomes Helen I. Keen Paul Emery Philip G. Conaghan Osteoarthritis (OA) is increasingly common in our aging society. Cartilage is not the only anatomic structure involved…
Radiologic Diagnosis Garry Gold Vijay Chandnani Donald Resnick The term osteoarthritis (OA), previously called degenerative joint disease, is applied to a variety of distinct processes affecting joints in extraspinal and…
Osteoarthritis: Clinical Presentations Michele M. Hooper Roland W. Moskowitz The symptomatic osteoarthritic joint presents with pain, limited range of motion, and stiffness; but symptoms are highly variable, depending on which…
Molecular Genetics of Osteoarthritis John Loughlin Kay Chapman Outline There has long been a suspicion that genes play a role in the development of osteoarthritis (OA). However, it is only…
Experimental Models of Osteoarthritis Margaret M. Smith Christopher B. Little Although the etiopathogenesis of osteoarthritis (OA) is still the subject of intense debate and research, its pathology is well established.1…
Cell Biology, Biochemistry, and Molecular Biology of Articular Cartilage in Osteoarthritis Linda J. Sandell Dick Heinegard Thomas M. Hering Cartilage: Tissue Organization Articular cartilage is comprised largely of an extracellular…
Pathology of Osteoarthritis Aubrey J. Hough Jr. Historical Concepts of Osteoarthritis Medical science is to a degree inseparable from its ancient origins in so-called natural philosophy. Disease itself was originally…
