Spondyloarthritis
Axial SpA Peripheral SpA Back pain ≥3 months Age of onset <45 years Peripheral arthritis and/or enthesitis and/or dactylitis and either column below Sacroiliitis on imaging (Acute inflammation on MRI OR definite…
Genetics in Rheumatology
Classification Clinical features Gene/chromosome/OMIM Protein Inheritance Monogenic periodic fevers Familial Mediterranean fever (FMF) Recurrent febrile episodes with serositis and arthritis. Long-term development of AA amyloidosis in untreated patients. Good clinical…
Rheumatology for Adult Rheumatologists
!DOCTYPE html> © Springer Nature Switzerland AG 2020P. Efthimiou (ed.)Absolute Rheumatology Reviewhttps://doi.org/10.1007/978-3-030-23022-7_17 17. Pediatric Rheumatology for Adult Rheumatologists Natalie Rosenwasser1 and Karen Onel2 (1) University of Washington, Seattle, SA, USA (2) Hospital for Special Surgery,…
12. Vasculitis
Fig. 12.1 Giant cell arteritis. The wall of this muscular artery is diffusely involved by granulomatous inflammation, including scattered multinucleated giant cells, with significant loss of the muscular media and…
Sclerosis (Scleroderma)
Cell Pathogenic effects Fibroblasts Produce collagen and other extracellular matrix molecules Adipocytes, endothelial cells, epithelial cells Undergo transition to myofibroblasts expressing a smooth actin and producing collagen T cells Are…
3. Osteoarthritis
Fig. 3.1 OA pathophysiology. The pathophysiology of OA involves a variety of systemic and local factors, including trauma, aging, obesity, epigenetic, and genetic factors. Chronic inflammation plays a strong role,…
Mobile Bearing in Unicompartmental Knee Arthroplasty
Fig. 8.1 The current design of the mobile-bearing Oxford, marketed as the Oxford Twin Peg Partial Knee, was initially introduced in 2003 in the United Kingdom and later implemented worldwide….
Unicompartmental Knee Arthroplasty: Indications and Technique
Fig. 9.1 Anteroposterior, lateral, and patellar view of a 66-year-old patient with left knee pain that is recalcitrant to nonoperative measures. There is lateral joint space narrowing, preserved medial compartment,…
Unicompartmental Knee Arthroplasty for More than One Compartment
Fig. 11.1 Preoperative radiographs of the left knee including (a) standing AP, (b) standing flexion 45-degree PA, (c) lateral and (d) sunrise views. These radiographs demonstrate degenerative changes including medial…
