Piero Picci, Marco Manfrini, Nicola Fabbri, Marco Gambarotti and Daniel Vanel (eds.)Atlas of Musculoskeletal Tumors and Tumorlike Lesions2014The Rizzoli Case Archive10.1007/978-3-319-01748-8_43 © Springer International Publishing Switzerland 2014 43. Biology of Osteosarcoma Massimo Serra1 (1) Laboratory of Experimental Oncology, Istituto…
Chondrosarcomas varieties % Central 55–60 Peripheral 15–20 Dedifferentiated central
Piero Picci, Marco Manfrini, Nicola Fabbri, Marco Gambarotti and Daniel Vanel (eds.)Atlas of Musculoskeletal Tumors and Tumorlike Lesions2014The Rizzoli Case Archive10.1007/978-3-319-01748-8_32 © Springer International Publishing Switzerland 2014 32. Biology of Central and Peripheral Chondrosarcoma Maria Serena Benassi1 (1) Laboratory of…
Histologically the tumor is very similar to enchondroma, but it more frequently displays features of cell proliferation (high cellularity, nuclear plumpness, and frequent double-nucleated cells). Being somewhat painful and causing…
In Maffucci’s syndrome (very rare), multiple, diffuse chondromas are associated with multiple hemangiomas, cutaneous, subcutaneous, or in the deep soft tissues (not in the bone). Basic imaging is the same…
Localization: It usually arises in the metaphyses of the long bones, beneath the growth plate, but along with patient growth, the cyst migrates to the diaphysis. The most common location…
Location: Femur (proximal), tibia, craniofacial bones, ribs; then humerus, forearm, pelvis. Same sites in multicentric and polyostotic disease. Frequently more areas in the same long bone, or two to three…
Piero Picci, Marco Manfrini, Nicola Fabbri, Marco Gambarotti and Daniel Vanel (eds.)Atlas of Musculoskeletal Tumors and Tumorlike Lesions2014The Rizzoli Case Archive10.1007/978-3-319-01748-8_21 © Springer International Publishing Switzerland 2014 21. Biology of Giant Cell Tumor Maria Serena Benassi1 (1) Laboratory of Experimental…
Radiographs of the arm and hand. Multiple exostoses. Bone deformation and shortening Selected Bibliography Bovée JV (2008) Multiple osteochondromas. Orphanet J Rare Dis 3:3. ReviewPubMedCentralPubMedCrossRef
Localization: The lesion is almost exclusively localized in the shaft of the tibia, occasionally involving the ipsilateral fibula, too. Exceptionally it is bilateral in tibias and fibulas. Clinical: The symptoms…
