Variation in Range of Movement Reporting in Dupuytren Disease

Oct 4, 2017 by in ORTHOPEDIC Comments Off on Variation in Range of Movement Reporting in Dupuytren Disease

PICOS analysis Definition Participants Dupuytren Disease of the hand Intervention Surgical treatment/percutaneous fasciotomy/collagenase injection for DD Comparisons Not applicable (systematic review) Outcomes Reported range of movement Study design Included: RCTs,…

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Prospective Multicenter, Multinational Study to Evaluate the Safety and Efficacy of Concurrent Collagenase Clostridium Histolyticum Injections to Treat Two Dupuytren Contractures in the Same Hand

Oct 4, 2017 by in ORTHOPEDIC Comments Off on Prospective Multicenter, Multinational Study to Evaluate the Safety and Efficacy of Concurrent Collagenase Clostridium Histolyticum Injections to Treat Two Dupuytren Contractures in the Same Hand

Fig. 18.1 Mean flexion contractures from baseline to day 31 Fig. 18.2 Range of motion at baseline and day 31 Table 18.1 Most common treatment-related AEs AE, n (%) (n…

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The Extracellular Matrix in Dupuytren Disease

Oct 4, 2017 by in ORTHOPEDIC Comments Off on The Extracellular Matrix in Dupuytren Disease

Examples of molecules previously identified in the Dupuytren Disease extracellular matrix Structural and nonstructural ECM molecules Matricellular (nonstructural) ECM molecules Growth and differentiation factors Collagens (I, III, + many others)…

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