Author Lermusiaux et al. (2001) Foucher et al. (2003) Van Rijssen et al. (2006) Pess et al. (2012) Hurst et al. (2009) PNF PNF PNF PNF CCH SAE Tendon…
Fig. 19.1 Risk matrix 19.4.5 Recurrence as an Outcome Measure This poses a particular problem. There is no accepted definition of recurrence. A recurrence may hold different value after different…
Fig. 15.1 Experienced pain during injection and interval. Mean visual analog scale (VAS) scores for pain experienced during the first injection (buffered mepivacaine in the local anesthesia [LA] group; collagenase…
Injectable clostridial collagenase is a promising treatment for patients with Dupuytren contracture. Dose-ranging, phase 2 clinical trials identified an optimal collagenase dose of 10,000 units (0.58 mg), balancing excellent clinical…
Fig. 8.1 Dupuytren myofibroblasts. (a) Immunofluorescence staining of Dupuytren myofibroblasts in a 3D collagen matrix. Cell matrix junctions stained for integrin β1 (red), F actin (phalloidin) (green) and nuclei stained…
Fig. 12.1 From genotype to phenotype. Human genetic studies of Dupuytren Disease aim to identify the underlying genetic variation (genotype) contributing to the etiology of the disease (phenotype). The disease…
Fig. 2.1 The rate of surgery for Dupuytren contracture in the 143 NHS hospitals in England. The figure shows the different rates per 100,000 population, not standardised for age or…
© Springer International Publishing Switzerland 2017Paul M. N. Werker, Joseph Dias, Charles Eaton, Bert Reichert and Wolfgang Wach (eds.)Dupuytren Disease and Related Diseases – The Cutting Edge10.1007/978-3-319-32199-8_1 1. Treatment of Dupuytren Disease in Different Countries: A Welcome Address…
Fig. 12.1 Accepted metabolic effects of AMPK in skeletal muscle. AMPK is activated by several metabolic stresses such as energy depletion, myokines, adipokines, oxidative stress, and Ca2+ release from sarcoplasmic…
Author, year Journal, volume, pages Manner of analysis Results Species Andrianjafiniony etal. [41] Am J Physiol Cell Physiol 299: C307–C315 Western blot Beclin-1 protein ⇔ Mouse Liu et al. [42]…
