© Springer Science+Business Media Singapore 2017Sujata Sawhney and Amita Aggarwal (eds.)Pediatric Rheumatology10.1007/978-981-10-1750-6_8 8. Biologic Response Modifiers in Pediatric Rheumatology Alessandro Consolaro1 and Nicola Ruperto2 (1) Istituto Giannina Gaslini, University of Genova and Second Division of Pediatrics, Genova,…
Drug Dose (mg/kg/day unless otherwise noted) Maximal dose (mg/day) Doses per day Remarks Acetylsalicylic acid (ASA) 80–100 (<25 kg); 2500 mg/m2 (>25 kg) Antiplatelet dose 3–5 mg/kg/day single dose 4900…
Fig. 1.1 An example of recent advances in pediatric rheumatology (From Infevers: an online database for autoinflammatory mutations. Copyright. Available at http://fmf.igh.cnrs.fr/ISSAID/infevers/. Accessed April 13, 2016) That indeed is progress….
Chr SNP Best p value OR SNP position PTPN22a 1 rs6679677 3.2 × 10−25 1.59 Intergenic ATP8B2-IL6R 1 11265608 2.8 × 10−8 1.33 Intergenic STAT4 2 Rs10174238 1.3 ×…
Fig. 6.1 An example of a trial with withdrawal design. In part I, patients are treated in an open-label fashion with the experimental therapy. In part II, only responders to…
Publication year Reference Authors District Case ascertainment JIA etc. Max (years) Prev. cases Prev per 100,000 Prev 95 % C.I. A.I.* per 100,000 1992 [3] Andersson Gare and Fasth Southwest…
Fig. 21.1 The area of maximum bowstringing is the best location for PNF portals and for collagenase injection. (a) Pre-PNF, (b) post-PNF, (c) pre-CCH, (d) post-CCH 21.2 Technique: Percutaneous Needle…
Fig. 51.1 Current procedure options for Dupuytren contracture. Recommendations are based on the physician’s qualitative assessment of both the severity of contracture and the biologic severity of disease. This shows…
Fig. 9.1 Normal palmar aponeurosis. (a) Transverse section palmar aponeurosis. The skin is on the left side. Collagen fiber bundles ascend to the skin between fat lobules forming a three-dimensional…
Fig. 35.1 Patient selection flowchart. CCH clostridium collagenase histolyticum, LF limited fasciectomy, MHQ Michigan Hand Outcomes Questionnaire Table 35.1 shows the baseline characteristics of the study sample before and after…
