Clinical Case Vignettes: Vasculitis
Fig. 42.1 Purpuric papules over the tip of the toes in a 9-year-old girl Complete blood count, prothrombin time, partial thromboplastin time, and fibrinogen level were within normal limits. The…
Pediatric Vasculitis: Classification and Clinical Approach
Fig. 33.1 Palpable purpura over the left leg of a 10-year-old boy with IgAV/HSP This patient is a typical example of a child with severe IgA vasculitis (IgAV; formerly Henoch-Schönlein…
Clinical Case Vignettes: Connective Tissue Diseases in Children
Fig. 32.1 Calcinotic nodules in a child with juvenile dermatomyositis At the end of 6-year follow-up, her muscle weakness was in remission for >2 years, and methotrexate could be completely…
Infections and Arthritis in Childhood
Fig. 21.1 Sweling around lateral malleolus of right ankle with MRI of the region and ulcreated positive Mantoux test. (a) The arrow shows swelling and erythema around the lateral malleolus….
Outcome Measures in Pediatric Rheumatology
Disease status Parameters to be fulfilled per the JIA subcategory Inactive disease No active arthritis No fever, rash, serositis, splenomegaly, or generalized lymphadenopathy attributable to JIA No active uveitis Normal…
Transition: Moving from Pediatric to Adult Rheumatology Care
Pediatric Adult Triadic or family consultation Dyadic or individual consultation Assumes patient dependence Assumes patient independence Multidisciplinary team Limited multidisciplinary team Consultation time longer Consultation time shorter Procedural pain management…
Biologic Response Modifiers in Pediatric Rheumatology
© Springer Science+Business Media Singapore 2017Sujata Sawhney and Amita Aggarwal (eds.)Pediatric Rheumatology10.1007/978-981-10-1750-6_8 8. Biologic Response Modifiers in Pediatric Rheumatology Alessandro Consolaro1 and Nicola Ruperto2 (1) Istituto Giannina Gaslini, University of Genova and Second Division of Pediatrics, Genova,…
Nonbiologic Drugs in Pediatric Rheumatology
Drug Dose (mg/kg/day unless otherwise noted) Maximal dose (mg/day) Doses per day Remarks Acetylsalicylic acid (ASA) 80–100 (<25 kg); 2500 mg/m2 (>25 kg) Antiplatelet dose 3–5 mg/kg/day single dose 4900…
History of Pediatric Rheumatology
Fig. 1.1 An example of recent advances in pediatric rheumatology (From Infevers: an online database for autoinflammatory mutations. Copyright. Available at http://fmf.igh.cnrs.fr/ISSAID/infevers/. Accessed April 13, 2016) That indeed is progress….
Genetics of Pediatric Rheumatic Diseases
Chr SNP Best p value OR SNP position PTPN22a 1 rs6679677 3.2 × 10−25 1.59 Intergenic ATP8B2-IL6R 1 11265608 2.8 × 10−8 1.33 Intergenic STAT4 2 Rs10174238 1.3 ×…
