Impaired Parathyroid Function and Bone Formation: A Risk for Development of Adynamic Bone Disease to Enhance Vascular Calcification

Jul 3, 2016 by in MUSCULOSKELETAL MEDICINE Comments Off on Impaired Parathyroid Function and Bone Formation: A Risk for Development of Adynamic Bone Disease to Enhance Vascular Calcification

Glycemic control HbA1C GA Excellent (HbA1C≤6 %, GA≤18 %) 307 (57.1 %) 152 (28.3 %) Good (6 %<HbA1C≤7 %, 18 %<GA≤21 %) 128 (23.7 %) 106 (19.7 %) Good (7 %<HbA1C≤8 %, 21 %<GA≤24 %) 65 (12.1 %) 84 (15.6 %) Poor (8 %<HbA1C, 24 %<GA) 38 (7.1 %)…

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Bone as an Endocrine Organ: Diabetic Bone Disease as a Cause of Endocrine Disorder via Osteocalcin, FGF23 Secreted from Osteocyte/Osteoblast

Jul 3, 2016 by in MUSCULOSKELETAL MEDICINE Comments Off on Bone as an Endocrine Organ: Diabetic Bone Disease as a Cause of Endocrine Disorder via Osteocalcin, FGF23 Secreted from Osteocyte/Osteoblast

Fig. 8.1 Diabetes and bone-generated hormone interaction via osteoblast/osteocyte impairment. Several factors associated with diabetes impair osteoblast/osteocyte differentiation and function where FGF23 and osteocalcin were generated. AGEs advanced glycation end…

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Overview

Jul 3, 2016 by in MUSCULOSKELETAL MEDICINE Comments Off on Overview

Fig. 9.1 The factors that affect to GLUT4 translocation and glucose utilization in the skeletal muscle The working mechanism of insulin resistance is complex, probably involving numerous factors, including defective…

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Ectopic Fat Accumulation and Glucose Homeostasis: Role of Leptin in Glucose and Lipid Metabolism and Mass Maintenance in Skeletal Muscle

Jul 3, 2016 by in MUSCULOSKELETAL MEDICINE Comments Off on Ectopic Fat Accumulation and Glucose Homeostasis: Role of Leptin in Glucose and Lipid Metabolism and Mass Maintenance in Skeletal Muscle

Fig. 14.1 Schematic representation of the leptin’s effects on glucose and lipid metabolism in skeletal muscle Recent studies have extended our understanding of the role of leptin in obesity and…

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Sarcopenia in Diabetes Mellitus

Jul 3, 2016 by in MUSCULOSKELETAL MEDICINE Comments Off on Sarcopenia in Diabetes Mellitus

Fig. 16.1 Interaction between sarcopenia and diabetes. Insulin resistance in skeletal muscle is the most important link between sarcopenia and diabetes. Sarcopenia and obesity appear to have additive effects on…

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