Clinical Perspectives on Lupus Genetics

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Clinical Perspectives on Lupus Genetics

In recent years, genome-wide association studies have led to an expansion in the identification of regions containing confirmed genetic risk variants within complex human diseases, such as systemic lupus erythematosus…

read more

Systemic Lupus Erythematosus

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Systemic Lupus Erythematosus

Ellen M. Ginzler, MD, MPH, Editor Mary Anne Dooley, MD, MPH, Editor The last issue of Rheumatic Disease Clinics of North America to cover systemic lupus erythematosus (SLE) was published…

read more

Prediction of Future Rheumatoid Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Prediction of Future Rheumatoid Arthritis

Rheumatoid arthritis (RA) results from an interaction between genetic susceptibility and environmental factors. Several of these factors are known, such as family history of RA, high birth weight, smoking, silica…

read more

Prevention of Rheumatic Diseases

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Prevention of Rheumatic Diseases

Rheumatic diseases affect a significant portion of the population and lead to increased health care costs, disability, and premature mortality; effective preventive measures for these diseases could lead to substantial…

read more

Identification of Self-antigen–specific T Cells Reflecting Loss of Tolerance in Autoimmune Disease Underpins Preventative Immunotherapeutic Strategies in Rheumatoid Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Identification of Self-antigen–specific T Cells Reflecting Loss of Tolerance in Autoimmune Disease Underpins Preventative Immunotherapeutic Strategies in Rheumatoid Arthritis

Despite treatment advances, rheumatoid arthritis (RA) is still associated with significant disability, decreased work capacity, and reduced life expectancy. Effective immunotherapies to restore immune tolerance promise greater specificity, lower toxicity,…

read more
Premium Wordpress Themes by UFO Themes