Multiple Myeloma
Localization: The axial skeleton is the preferred site. In the appendicular skeleton, the metaepiphyses are preferred. Very rare in bones of the hand and foot. Clinical: Pain (usually relieved by…
Peripheral (Secondary) Chondrosarcoma
Imaging: On x-ray – typical aspect of an osteochondroma with more abundant calcifications or ossifications, intense, and diffused radiopacities, with thicker superficial uncalcified layer and with fuzzy margins towards the…
Extraskeletal Ewing’s Sarcoma
Location: Any soft tissue site can be involved, but most common are the paravertebral region, retroperitoneum, and chest wall, followed by the extremities. Clinical: Large, destructive mass. Histopathology: Grossly it…
Extraskeletal Osteosarcoma
Location: Deep soft tissues of the thigh and buttocks. Clinical: Progressively enlarging painless mass. Imaging: X-rays, CT, and MRI reveal a large deep-seated soft tissue mass with variable mineralization. By…
Epithelioid Sarcoma
Location: Among the most frequent sarcomas occurring in the hand and forearm. Palmar region of the hand, dorsal region of the forearm, plantar aspect of the foot, anterior region of…
Myxofibrosarcoma
Location: The most frequent sites are the lower limbs, followed by upper limbs and limb girdles. Rare in trunk, head and neck, and hands and feet. Most cases described in…
Solitary Fibrous Tumor
Location: Lower limb (thigh), retroperitoneum, pelvic region, upper limb, trunk, head, and neck. Deeply located. Clinical: Slow enlarging painless mass, increased skin temperature, telangiectasia, unilateral varicose veins, pulsation, audible bruit,…
Adamantinoma
Localization: Diaphysis of the long bones. The tibia is affected in 80 % of cases. Followed by the fibula, femur, humerus, ulna, and radius. Exceptional in the soft tissues of…
Dermatofibrosarcoma Protuberans
Location: Trunk, groin, and proximal extremities. Clinical: Nodular or plaque-like painless cutaneous tumor, slowly growing. Diagnosis: A well-defined superficial tumor. On MRI, in T1 usually iso- or hypointense to skeletal…
Extra-abdominal Fibromatosis
Clinical: Deep, painless, firm or hard, and poorly circumscribed mass that may be adherent to the skin or bone and that grows insidiously and slowly for several months. Tumor mass…
