Subsets of Osteoarthritis Generalized osteoarthritis Early epidemiological studies using radiological surveys detailed the fact that many patients had osteoarthritis of multiple joints, suggesting a generalized, in-built predisposition (3.1). Furthermore, the…
Principles of Management Introduction In the management of osteoarthritis, there are several tools available (5.1). There are a wide number of options, including non-pharmacological, pharmacological, and surgical options, which may…
Introduction What is osteoarthritis? The answer to this apparently simple question is an ongoing problem for a condition that is so common. Everyone seems to be able to recognize ‘osteoarthritis’…
General Features of Osteoarthritis What are the clinical features of osteoarthritis? The clinical features of osteoarthritis relate to both symptoms and signs. As has been discussed in Chapter 1, the…
Management of Osteoporosis Introduction Bone loss with ageing is universal and many will become osteoporotic in later life with increased risk of fracture. Measures therefore need to be taken by…
Future Therapeutic Options Paul D. Miller Current osteoporosis therapies have been shown to reduce the risk of fragility fractures generally from 50% to 65% over a period of 3 years….
Clinical Cases Pauline M. Camacho Paul D. Miller Case 1 History A 61-year-old white woman had a dual-energy x-ray absorptiometry (DXA) scan ordered by her primary-care physician. Other than mild…
Tailoring Therapy to Individual Patients Paul D. Miller The pharmacological agents for the prevention and treatment of postmenopausal osteoporosis (PMO) registered with the Food and Drug Administration (FDA) are listed…
Determining Success of Therapy and What to Do When Therapy Fails Paul D. Miller Osteoporosis therapies are designed to improve bone strength and reduce the risk for fracture. When the…
Treatment Options Pauline M. Camacho The National Osteoporosis Foundation has outlined clinical recommendations regarding initiation of therapy for low bone mass and osteoporosis (Table 8.1). According to their guidelines, treatment…
