Chapter 10 Allograft Particulate Cartilage Transplantation: DeNovo Natural Tissue (NT) Graft Jack Farr Introduction: DeNovo NT Graft The DeNovo Natural Tissue (NT) Graft is derived from articular cartilage allograft.1,2 The…
Chapter 5 Osteochondral Mosaicplasty László Hangod, Gábor Vásárhelyi, László Rudolf Hangody Introduction Full-thickness defects of weight-bearing articular surfaces have poor healing capacity and cause pain, effusion, and impaired joint function….
Chapter 11 Cartilage Fragment Implantation Mats Brittberg Introduction The Cartilage Autograft Implantation System (CAIS) is a kit that utilizes morselized autologous hyaline cartilage harvested arthroscopically, affixed onto a synthetic, resorbable…
Chapter 9C Autologous Chondrocyte Implantation ACI First and Second Generation Mats Brittberg Introduction Autologous chondrocyte implantation (ACI) is another means of repairing damaged cartilage.1 It is based on harvest of…
Chapter 15 Bone Grafting around an Articular Joint Marcus Head, James B. Richardson Introduction No substitute has been proven to be better than autograft. Bone is formed by stem cells,…
Chapter 9B Autologous Chondrocyte Implantation Quality Assurance of Cells for Chondrogenic Implantation Stephen J. Duguay Introduction High-quality chondrocytes are essential for successful autologous chondrocyte implantation (ACI) outcomes. Cell therapy manufacturers…
Chapter 9A Cartilage Biopsy Handling Anders Lindahl, Sebastian Concaro Cartilage Biopsy and Handling The technology of autologous chondrocyte transplantation is based on the use of autologous cartilage for cell processing….
Chapter 4C Bone Marrow Stimulating Techniques Autologous Matrix-Induced Chondrogenesis (AMIC) Peter Behrens, J.P. Benthien Introduction Chondral and osteochondral defects may affect any major joint, but they more often affect the…
Chapter 2 Patient Evaluation and Treatment Algorithms Marco Delcogliano, Jason Boyer, Bert R. Mandelbaum Introduction The clinical consequences of articular cartilage defects of the knee are pain, swelling, mechanical symptoms,…
