A male patient was diagnosed at 48 years of age with Wegener’s granulomatosis (WG) involving the sinuses, nose, and lungs. He was treated with daily cyclophosphamide and prednisolone for 1…
Systemic sclerosis or scleroderma (SSc) is a rare and complicated autoimmune disease that presents with many challenging therapeutic quandaries. In this chapter, we will discuss and examine these frequently encountered…
INTRODUCTION The antiphospholipid syndrome (APS) is the association of thrombosis, pregnancy loss, and morbidity, and certain other clinical manifestations with antiphospholipid antibodies (aPLs) (lupus anticoagulant [LA], anticardiolipin antibodies [aCL], and/or…
INTRODUCTION Renal involvement is one of the most serious clinical manifestations of systemic lupus erythematosus (SLE), contributing significantly to overall morbidity and mortality. Its prevalence in lupus varies from 31%…
INTRODUCTION Systemic lupus erythematosus (SLE) is a multisystem, inflammatory disorder. Its treatment warrants general anti-inflammatory measures as well as organ-specific, preventive, or focused measures concentrating on sets of commonalities. The…
INTRODUCTION Systemic lupus erythematosus (SLE) is an inflammatory systemic autoimmune disorder that has a very wide ranging spectrum of clinical manifestations as well as varied clinical course. It is characterized…
Juvenile rheumatoid arthritis (JRA) is an umbrella term for a number of arthritides of unknown etiology that occur in children younger than 16 years of age. It is the most…
CASE 1 A 28-year-old man was referred to the psoriatic arthritis (PsA) clinic because of swollen toes. He developed a swollen left toe 6 to 7 years prior and was…
Ankylosing spondylitis (AS) is the most prototypic of a group of arthritides collectively known as spondyloarthritis (SpA) that are associated with the human leukocyte antigen B27 (HLA B27). The hallmarks…
CASE STUDY 1 The patient was a 62-year-old woman with long-standing rheumatoid arthritis (RA), who was admitted to a tertiary center because of increasing disability and fatigue. She had been…
