Glucocorticoid-induced Osteoporosis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Glucocorticoid-induced Osteoporosis

Glucocorticoid-induced osteoporosis (GIOP) is one of the most common and serious adverse effects associated with glucocorticoid use. This article highlights GIOP pathophysiology, epidemiologic associations, effective treatment, and lifestyle modifications that…

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Infection Risk and Safety of Corticosteroid Use

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Infection Risk and Safety of Corticosteroid Use

Corticosteroids are frequently used to treat rheumatic diseases. Their use comes with several well-established risks, including osteoporosis, avascular necrosis, glaucoma, and diabetes. The risk of infection is of utmost concern…

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Corticosteroids in Sarcoidosis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Corticosteroids in Sarcoidosis

Corticosteroids are the drug of choice for the treatment of sarcoidosis. Because the natural course of sarcoidosis may be self-limiting and/or cause no long-term harm, treatment is not mandatory. Corticosteroids…

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Corticosteroids in Myositis and Scleroderma

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Corticosteroids in Myositis and Scleroderma

Idiopathic inflammatory myopathies (IIMs) involve inflammation of the muscles and are classified by the patterns of presentation and immunohistopathologic features on skin and muscle biopsy into 4 categories: dermatomyositis, polymyositis,…

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Corticosteroids for Pain of Spinal Origin

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Corticosteroids for Pain of Spinal Origin

Targeted interventional delivery of corticosteroids remains a mainstay of treatment for spinal pain syndromes because this approach has a wider therapeutic index than other approaches. The best evidence for analgesic…

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Corticosteroids in Lupus

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Corticosteroids in Lupus

Corticosteroids are the mainstay of treatment of systemic lupus erythematosus, with most patients receiving them at some point in the course of their disease. Corticosteroid use is associated with significant…

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Glucocorticoids and Rheumatoid Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Glucocorticoids and Rheumatoid Arthritis

Glucocorticoids (GCs) were discovered in the 1940s and were administered for the first time to patients with rheumatoid arthritis in 1948. However, side effects were subsequently reported. In the last…

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