Early Psoriatic Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Early Psoriatic Arthritis

Skin psoriasis is a major risk factor for the development of psoriatic arthritis. Recent studies have shown that delayed diagnosis is associated with long-term adverse outcomes. Screening questionnaires have revealed…

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Comorbidities in Psoriatic Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Comorbidities in Psoriatic Arthritis

Epidemiologic studies have shown that, in patients with psoriatic arthritis (PsA), associated comorbidities may occur more frequently than expected. This article discusses related comorbidities in patients with PsA. Identifying these…

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Management of Psoriatic Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Management of Psoriatic Arthritis

Traditional disease-modifying antirheumatic drugs (DMARD) remain the first-line treatment of psoriatic arthritis (PsA), despite lack of randomized controlled trials, and with evidence based on observational studies. Anti-tumor necrosis factor agents…

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Novel Treatment Concepts in Psoriatic Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Novel Treatment Concepts in Psoriatic Arthritis

The introduction of highly effective therapies and clearly defined targets has altered the treatment paradigm in psoriatic arthritis (PsA). Validated classification criteria and outcome measures specific to PsA have helped…

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Biologic Therapy for Psoriatic Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Biologic Therapy for Psoriatic Arthritis

Biologic medications, therapeutic proteins that inhibit or modulate proinflammatory immune cells and cytokines, have significantly altered clinicians’ ability to effectively treat psoriatic arthritis (PsA). The first widely used biologics have…

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Outcome Measures in Psoriatic Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Outcome Measures in Psoriatic Arthritis

In the last decade, there have been significant advances in outcome measure research in psoriatic arthritis (PsA). In this article, the outcome measures for disease activity in individual key domains…

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Etiology and Pathogenesis of Psoriasis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Etiology and Pathogenesis of Psoriasis

Psoriasis is a common, chronic inflammatory skin disease most often appearing in the form of well-demarcated, scaly plaques. These lesions highlight the fundamental processes underlying its pathogenesis, namely, inflammation and…

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Etiology and Pathogenesis of Psoriatic Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Etiology and Pathogenesis of Psoriatic Arthritis

The current model of psoriatic arthritis implicates both the IL-23/IL-17 axis and the tumor necrosis factor (TNF) pathways in disease pathogenesis. Although specific major histocompatibility complex class I molecules are…

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Imaging in Psoriatic Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Imaging in Psoriatic Arthritis

Psoriatic arthritis (PsA) is an inflammatory joint disease characterized by arthritis and often enthesitis in patients with psoriasis, presenting a wide range of manifestations in various patterns. Imaging procedures are…

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