Lipid-Associated Rheumatologic Syndromes

Oct 1, 2017 by in RHEUMATOLOGY Comments Off on Lipid-Associated Rheumatologic Syndromes

Rheumatologic manifestations of hyperlipidemia and lipid-associated arthritis are rarely seen in the rheumatologist’s office. On the other hand, a rheumatologist may be the clinician who identifies and initiates proper therapy…

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Noninflammatory Myopathies

Oct 1, 2017 by in RHEUMATOLOGY Comments Off on Noninflammatory Myopathies

The noninflammatory myopathies are a diverse group of diseases, some of which may mimic the autoimmune-mediated idiopathic inflammatory myopathies in their clinical presentation. They include certain metabolic, toxic, and infectious…

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Joint Hypermobility Syndrome

Oct 1, 2017 by in RHEUMATOLOGY Comments Off on Joint Hypermobility Syndrome

Although perceived as a rare condition, joint hypermobility syndrome is common. Its prevalence in rheumatology clinics is extremely high. Early estimates suggest that it may be the most common of…

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SAPHO Syndrome

Oct 1, 2017 by in RHEUMATOLOGY Comments Off on SAPHO Syndrome

SAPHO syndrome is a disorder characterized by S ynovitis, A cne, P ustulosis, H yperostosis, and O steitis. As the osteoarticular and skin manifestations often do not occur simultaneously and…

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Retroperitoneal Fibrosis

Oct 1, 2017 by in RHEUMATOLOGY Comments Off on Retroperitoneal Fibrosis

Retroperitoneal fibrosis (RPF) is a condition characterized by the presence of inflammation and fibrosis in the retroperitoneal space, for which no standard diagnostic criteria exist. Historically, treatment has focused on…

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Hypertrophic Osteoarthropathy

Oct 1, 2017 by in RHEUMATOLOGY Comments Off on Hypertrophic Osteoarthropathy

This article presents an updated overview of hypertrophic osteoarthropathy and digital clubbing for the practicing rheumatologist. Discussion includes a brief historical perspective, its definition, incidence and prevalence, classification, pathology and…

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Localized Cutaneous Fibrosing Disorders

Oct 1, 2017 by in RHEUMATOLOGY Comments Off on Localized Cutaneous Fibrosing Disorders

This article acquaints the reader with disorders of the skin that might mimic systemic sclerosis but whose pathology is localized to the skin and/or has extracutaneous manifestations that are different…

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Amyloidosis

Oct 1, 2017 by in RHEUMATOLOGY Comments Off on Amyloidosis

Amyloidosis is the name for protein-folding diseases characterized by extracellular deposition of a specific soluble precursor protein that aggregates in the form of insoluble fibrils. The classification of amyloidosis is…

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Erdheim-Chester Disease

Oct 1, 2017 by in RHEUMATOLOGY Comments Off on Erdheim-Chester Disease

Erdheim-Chester disease (ECD) is a rare form of non-Langerhans’ cell histiocytosis. Diagnosis of ECD is based on the identification in tissue biopsy of histiocytes, which are typically foamy and immunostain…

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