The mother is the major source of circulating 25-OHD concentrations in the young infant. Thus maternal vitamin D status is an important factor in determining the vitamin D status of…
The unique cis -triene structure of vitamin D and related metabolites makes it susceptible to oxidation, ultraviolet (UV) light-induced conformational changes, heat-induced conformational changes, and attacks by free radicals. Vitamin…
The actions of the vitamin D hormone 1,25-dihydroxyvitamin D 3 (1,25(OH) 2 D 3 ) are mediated by the vitamin D receptor (VDR), a ligand-activated transcription factor that functions to…
The biologically active metabolite of vitamin D, 1,25(OH) 2 D 3 , affects mineral homeostasis and has numerous other diverse physiologic functions including effects on growth of cancer cells and…
