Sickle Cell Nephropathy
Sickle Cell Nephropathy Ewa Elenberg Children with sickle cell anemia, and often those with sickle cell trait, may present with a wide spectrum of significant urinary tract disorders, including hyposthenuria,…
Nephropathy of Diabetes Mellitus
Nephropathy of Diabetes Mellitus L. Leighton Hill Diabetes mellitus is the leading cause of end-stage renal disease (ESRD) worldwide. In the United States, diabetic nephropathy accounts for approximately 40% of…
Familial Juvenile Nephronophthisis
Familial Juvenile Nephronophthisis Ewa Elenberg Familial juvenile nephronophthisis (NPH), also termed nephronophthisis type 1 (NPH1), is an autosomal recessive, progressive tubulointerstitial kidney disease. It is characterized clinically by polyuria, polydipsia,…
Benign Familial Hematuria
Benign Familial Hematuria Ewa Elenberg Benign familial hematuria (BFH) also is known as benign persistent hematuria, benign essential hematuria, or thin basement membrane disease (TBMD). The term benign implies benign…
Progressive Hereditary Nephritis
Progressive Hereditary Nephritis Ewa Elenberg Alport syndrome or hereditary nephritis is characterized by hematuria, proteinuria, progressive renal failure, sensorineural hearing loss, and ocular lesions. Affected male patients typically have severe…
Glomerulonephritis and Nephrotic Syndrome
Glomerulonephritis and Nephrotic Syndrome Eileen D. Brewer OVERVIEW OF GLOMERULONEPHRITIS Glomerulonephritis (GN) is the general name given to a heterogenous group of diseases that result from immunologic injury to glomeruli…
Renal Malformations
Renal Malformations Laura S. Finn Developmental abnormalities of the kidney produce significant rates of morbidity and mortality and are the most common cause of renal failure in children. Malformations result…
End-Stage Renal Disease
End-Stage Renal Disease Edward C. Kohaut DIALYSIS Deciding when to initiate dialytic therapy in the child with chronic renal failure (CRF) often is difficult. No given level of serum creatinine…
Disorders of Renal Development and Anomalies of the Collecting System, Bladder, Penis, and Scrotum
Disorders of Renal Development and Anomalies of the Collecting System, Bladder, Penis, and Scrotum David R. Roth Edmond T. Gonzales DISORDERS OF RENAL DEVELOPMENT Abnormalities of Position Simple Ectopia Simple…
Chronic Renal Failure
Chronic Renal Failure Edward C. Kohaut During the late 1970s, whether any child was a candidate for any form of renal replacement therapy was questioned because the rigors of therapy…
