Cholecystitis
Cholecystitis Kathleen J. Motil Cholecystitis is an inflammatory disease of the gallbladder that may be acute or chronic. In some instances, acute cholecystitis may be superimposed on the preexisting chronic…
Liver Abscess
Liver Abscess Prathiba Nanjundiah William J. Klish Because the liver has systemic and portal circulations, the infrequency of liver abscess in infants and children is surprising. The low incidence is…
Disorders of the Liver and Biliary System
Disorders of the Liver and Biliary System Donald A. Novak Frederick J. Suchy William F. Balistreri Significant changes in hepatic anatomy and physiology occur in neonates. These rapid maturational alterations…
Pancreatitis
Pancreatitis Steven L. Werlin ACUTE PANCREATITIS Acute pancreatitis is most common pancreatic disorder in children, second only to cystic fibrosis in prevalence. Blunt abdominal trauma, viral infections (especially mumps), and…
Appendicitis
Appendicitis Walter Pegoli Jr. Appendicitis is the most common clinical entity leading to emergency abdominal operations in children. Pathologist Reginald Fitz initially described the condition in 1886. T. G. Morton…
Enzyme and Transport Defects
Enzyme and Transport Defects Sandy T. Hwang Robert J. Shulman CARBOHYDRATE MALABSORPTION Pathophysiology and Clinical Findings Disorders of carbohydrate absorption are linked integrally with dysfunction of the small-intestinal mucosal carbohydrate-digesting…
Immunodeficiency States
Immunodeficiency States Carlos H. Lifschitz ACQUIRED IMMUNODEFICIENCY SYNDROME The acquired immunodeficiency syndrome (AIDS) has been reported in children since 1983 and may be found among hemophiliacs, transfusion recipients, infants born…
Celiac Disease
Celiac Disease Carlos H. Lifschitz Celiac disease (CD) is an immune-mediated disease, characterized by villous atrophy of the proximal small bowel, that responds to the withdrawal of gluten from the…