Imaging of Osteochondritis Dissecans
Osteochondritis dissecans (OCD) is a localized process that affects the subchondral bone and can progress to the overlying articular cartilage. The cause of this lesion remains elusive. With the vague…
Structural and Functional Maturation of Distal Femoral Cartilage and Bone During Postnatal Development and Growth in Humans and Mice
The size and shape of joints markedly affect their biomechanical properties, but the macroscopic 3-dimensional (3-D) mechanism and extent of cartilage and joint maturation during normal growth are largely unknown….
Clinical Relevance of Scaffolds for Cartilage Engineering
The repair of articular cartilage defects in patients’ knees presents a particular challenge to the orthopedic surgeon because cartilage lacks the ability to repair or regenerate itself. Various cartilage repair…
Implantation of Orthobiologic, Biodegradable Scaffolds in Osteochondral Repair
The treatment of articular cartilage lesions is complicated, but novel tissue engineering approaches seem to improve the outcome. A tissue engineering approach is less invasive and reduces surgical time, periosteal…
Acute Traumatic and Sports-Related Osteochondral Injury of the Pediatric Knee
Adolescents are predisposed to osteochondral (OC) injuries in the knee. The medial facet of the patella, the femoral trochlea, and the lateral femoral condyle are the most common sites of…
“One Step” Treatment of Juvenile Osteochondritis Dissecans in the Knee: Clinical Results and T2 Mapping Characterization
Osteochondritis dissecans (OCD) is an increasingly common cause of knee pain and dysfunction among skeletally immature and young adult patients. An ideal treatment strategy with an optimal surgical technique to…
Epidemiology, Pathogenesis, and Imaging of Arthritis in Children
Juvenile idiopathic arthritis is a broad term used to describe a series of chronic arthritis occurring in children younger than 16 years of age. Even though the cause is not…
Epidemiology, Pathogenesis, and Imaging of Arthritis in Children
Juvenile idiopathic arthritis is a broad term used to describe a series of chronic arthritis occurring in children younger than 16 years of age. Even though the cause is not…
Effect of Exercise on Articular Cartilage
This review primarily focuses on how the macromolecular composition and architecture of articular cartilage and its unique biomechanical properties play a pivotal role in the ability of articular cartilage to…
Articular Cartilage Development: A Molecular Perspective
In this article, development of articular cartilage and endochondral ossification is reviewed, from the perspective of both morphologic aspects of histogenesis and molecular biology, particularly with respect to key signaling…
