51 Study Design
10.1055/b-0035-122051 51 Study Design Taco Johan Blokhuis Study design in experimental research is fundamentally different from study design in clinical research for several reasons. First, the question to be answered…
48 Use of Growth Factors in Musculoskeletal Research
10.1055/b-0035-122048 48 Use of Growth Factors in Musculoskeletal Research Iain R. Murray Growth factors (GFs) are naturally occurring substances that bind to receptors on the cell surface and are capable…
50 Biological Evaluation and Testing of Medical Devices
10.1055/b-0035-122050 50 Biological Evaluation and Testing of Medical Devices Dieter R. Dannhorn In order to exclude potential biological hazards or to control residual risks as much as possible, the consolidated…
34 Image Analysis Histomorphometry Stereology
10.1055/b-0035-122034 34 Image Analysis Histomorphometry Stereology Chuanyong Lu, Ralph Marcucio, and Theodore Miclau Jargon Simplified: Stereology Stereology is a method to get unbiased quantitative estimation of the first-order stereological parameters…
27 Ultrasound Techniques for Imaging Bone
10.1055/b-0035-122027 27 Ultrasound Techniques for Imaging Bone Thomas J. MacGillivray and Erin Ross Fracture recovery is currently assessed using a combination of physical assessment and X-ray. 1 The limitations of…
45 In Vivo Models for Articular Cartilage Repair
10.1055/b-0035-122045 45 In Vivo Models for Articular Cartilage Repair Paul Hindle The translation of basic science research requires rigorous investigation prior to human clinical trials. An important step in this…
32 Molecular Imaging In Situ Hybridization
10.1055/b-0035-122032 32 Molecular Imaging In Situ Hybridization Kishan Sokhi Aldridge and Roland Aldridge Molecular genetics describes the study of gene structure and function at its most basic level; it includes…
25 Micro-Computed Tomography Imaging of Bone Tissue
10.1055/b-0035-122025 25 Micro-Computed Tomography Imaging of Bone Tissue Timothy M. Jackman, Gabriel McDonald, and Elise F. Morgan Since the introduction of micro-computed tomography (µCT) for imaging of trabecular bone approximately…
33 Laser Scanning Confocal Microscopy and Laser Microdissection
10.1055/b-0035-122033 33 Laser Scanning Confocal Microscopy and Laser Microdissection Kwong-Man Lee Laser scanning confocal microscopy and laser microdissection are the most indispensable cell image acquisition and isolation tools incorporating advanced…
21 Validation of Finite Element Models
10.1055/b-0035-122021 21 Validation of Finite Element Models Luca Cristofolini While in natural sciences, empiricism is predominant, mathematical modeling is traditionally limited to inductive models that extrapolate from repeated experimental observations….
