Fibromyalgia and Sleep
Chronic pain in fibromyalgia patients, together with its associated symptoms and co-morbidities, is now considered a result of dysregulated mechanisms in the central nervous system (CNS). As fibromyalgia patients often…
RHEUMATOLOGY
Translational musculoskeletal pain research
Diagnosis and management of musculoskeletal pain is a major clinical challenge. Fundamental knowledge of nociception from deep somatic structures and related mechanisms of sensitisation have been characterised in animals but…
Trauma and work-related pain syndromes: Risk factors, clinical picture, insurance and law interventions
In the past decade, major progress has been made in our understanding of fibromyalgia syndrome (FMS). Various triggers have been implicated as contributing to symptom development in FMS when genetically…
Myofascial pain syndromes and their evaluation
This article reviews the available published knowledge about the diagnosis, pathophysiology and treatment of myofascial pain syndromes from trigger points. Furthermore, epidemiologic data and clinical characteristics of these syndromes are…
Epidemiology of chronic musculoskeletal pain
Chronic widespread pain (CWP) due to musculoskeletal conditions is a major social burden. The case definition of CWP relies on pain, chronicity (more than 3 months’ duration) and widespread distribution…
Chronic widespread pain in the spectrum of rheumatological diseases
Fibromyalgia (FM) is a rheumatic disease characterised by musculoskeletal pain, chronic diffuse tension and/or stiffness in joints and muscles, fatigue, sleep and emotional disturbances and pressure pain sensitivity in at…
Peripheral pain mechanisms in chronic widespread pain
Clinical symptoms of chronic widespread pain (CWP) conditions like fibromyalgia (FM), include pain, stiffness, subjective weakness, and muscle fatigue. Muscle pain in CWP is usually described as fluctuating and often…
Central pain mechanisms in chronic pain states – Maybe it is all in their head
Mechanisms underlying chronic pain differ from those underlying acute pain. In chronic pain states, central nervous system (CNS) factors appear to play particularly prominent roles. In the absence of anatomical…
Chronic widespread pain: From peripheral to central evolution
Chronic pain can be classified as localised, regional or widespread, and its high prevalence in the general population seems to increase with age. The majority of cases present with musculoskeletal…
Chronic widespread pain or fibromyalgia? That is the question
One of the tautological matters that bothers us when we participate with algologists in meetings concerning chronic pain is the idea that it is a syndrome per se and does…
