Th17 Cells: Differentiation and Regulation
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA 3.1 Identification of Th17 Cells The increased IL-17A production by CD4+ T cells from T…
RHEUMATOLOGY
Therapeutic Applications: Strategies and Molecules Targeting the IL-17/Th17 Pathway
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA As shown in Fig. 5.1a–e, there are multiple points where the interleukin 17 (IL-17)/Th17 pathway…
Overview of IL-17 Family
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA 1.1 Discovery and Structure of IL-17 The name of IL-17 was first proposed by Yao…
Concluding Remarks
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA The family of IL-17 cytokines is one of the most ancient cytokines that plays an…
IL-17 in Host Defense
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA 2.1 Cellular Source of IL-17 Many cell types including immune and nonimmune cells are able…
The Role of IL-17/Th17 Pathway in the Pathogenesis of Autoimmune Inflammatory Diseases
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA 4.1 Rheumatoid Arthritis Rheumatoid arthritis (RA) is characterized by chronic inflammation of the synovium and…
Imaging of the Clavicle
Fig. 4.1 AP axial radiograph of the left clavicle demonstrates a comminuted fracture with associated rib fractures and a moderate-sized pneumothorax (arrows) The standard AP view of the clavicle is…
Sternoclavicular Joint Injuries
Fig. 9.1 The intra-articular disk ligament (Held by forceps), costoclavicular ligament (Figure B arrowhead), capsular ligament (Figure B arrow), and interclavicular ligament lend integrity to the sternoclavicular joint Mechanism of…
Distal Clavicle and Medial Clavicle Fractures
Fig. 10.1 Serendipity radiographic view of bilateral SC joints. A malunion of the right medial clavicle is present although difficult to appreciate The interpretation of medial clavicle fractures using plain…
Evaluation of Clavicle Injuries
Fig. 3.1 Direct force mechanism for posterior SC dislocation Indirect Force Indirect force injuries are much more common with the energy force directed to the lateral aspect of the clavicle…
