Key Points • Cartilage calcification (chondrocalcinosis) can occur in both fibrocartilage and hyaline cartilage. Fibrocartilaginous calcifications are most common in the menisci of the knee, triangular fibrocartilage of the wrist,…
Key Points • Radiography is the main imaging modality for evaluation of progression of gout, but there is a 5- to 10-year latent period between first clinical symptoms and the…
Key Points • Assessment of nephrolithiasis, cholecystolithiasis, and ureteral calcified concrements has been the main indication for ultrasound in internal medicine. Ultrasound can detect uric acid–containing kidney stones that would…
Supported by the VA Research Service. Introduction This textbook has thoroughly covered the current status of gout clinical practice, a subject whose nuances, with respect to evidence-based medicine, have been…
Key Points • Basic calcium phosphate (BCP) crystals are a group of ultramicroscopic crystals that are mainly composed of hydroxyapatite and are frequently deposited in articular tissues. • BCP crystal…
Key Points • Rheumatic syndromes are a common complication of chronic kidney disease (CKD); regardless of renal disease etiology, musculoskeletal symptoms have been reported in up to 82% of patients…
Key Points • Calcium pyrophosphate dihydrate (CPPD) crystal deposition is a metabolic disorder that manifests substantially more often as joint pathology than it does as a symptomatic arthropathy. • The…
Key Points • There are a number of in vitro and in vivo models supporting a complex potential relation of hyperuricemia to both cardiovascular and renal outcomes. • Definitive evidence…
Key Points • By far the majority of calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is an idiopathic/sporadic disease with onset in later life, but early-onset familial disease also occurs….
Key Points • Despite the growing prevalence of gout, only a few studies have examined the overall impact of gout on patient’s health-related quality of life (HRQOL). HRQOL refers to…
