Jennifer L. Barton, MD, Editor Patricia Katz, PhD, Editor Historically, measurement of disease activity and response to therapy in the rheumatic diseases has presented significant challenges to clinicians, researchers, and…
Michael H. Weisman, MD, Consulting Editor Barton and Katz have assembled an issue that will be a standard reference for the near future. Their experts show clearly the value of…
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA www.rheumatic.theclinics.com Consulting Editor MICHAEL H. WEISMAN May 2016 • Volume 42 • Number 2
Sjögren’s disease is associated with a high burden of illness, diminished quality of life, and increased health care costs. The Sjögren’s Syndrome Foundation developed the first US clinical practice guidelines…
Sjögren syndrome (SS) comprises glandular and extraglandular manifestations. Double-blind prospective trials of traditional disease-modifying antirheumatic drugs and biologics have failed because they have not improved benign symptoms, the major cause…
Major salivary gland (SG) ultrasonography (US) represents a noninvasive, nonirradiating imaging modality for evaluation of the major SGs in the diagnosis and follow-up of primary and secondary Sjögren syndrome. Structural…
Salivary gland biopsy is a technique broadly applied for the diagnosis of Sjögren syndrome (SS), lymphoma in SS, and connective tissue disorders (sarcoidosis, amyloidosis). In SS characteristic histology findings are…
Primary Sjögren syndrome (pSS) can be considered a systemic autoimmune disease with a strong organ bias. The involvement of the exocrine glands is prevalent and drives the pathognomonic manifestations of…
Polyautoimmunity is defined as the presence of more than one well-defined autoimmune disease (AD) in a single patient. Polyautoimmunity is a frequent condition in Sjögren syndrome (SS) and follows a…
One of the main characteristics of primary Sjögren’s syndrome (pSS) is chronic dysfunction and destruction of the salivary and lacrimal glands; their secretory biofluids should reflect the glandular biological status….
