Abstract Patients with rheumatoid arthritis (RA) experience an increased cardiometabolic risk factor burden that is substantially driven by systemic inflammation. This occurs less consistently in patients with ankylosing spondylitis (AS)….

Abstract Dysregulation of the intestinal epithelial barrier in genetically susceptible individuals may lead to both intestinal and extraintestinal autoimmune disorders. There is emerging literature on the role of microbiota changes…

Abstract This chapter describes the involvement of the lung in systemic inflammatory joint disease (IJD) with a particular focus on rheumatoid arthritis, although the topics of pulmonary involvement in ankylosing…

Abstract Chronic inflammatory rheumatic diseases (IRD), including rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis, are prevalent conditions worldwide, with a considerable burden on healthcare systems. They are associated with increased…

Abstract The main orofacial manifestation of the inflammatory rheumatic diseases is that of Sjögren’s syndrome. In addition, there is a constellation of orofacial manifestations of the inflammatory rheumatic diseases, many…

Abstract In 30% of patients with fever or inflammation of unknown origin (FUO/IUO), the cause is eventually found to be a rheumatologic disease such as autoimmune or granulomatous disease or…

In the past two decades, the management and outcomes of inflammatory rheumatic diseases (IRDs) such as rheumatoid arthritis (RA), the spondyloarthropathies, psoriatic arthritis and ankylosing spondylitis have tremendously changed to…

Abstract Guidelines for low back pain (LBP) often recommend the use of self-management such as unsupervised exercise, booklets, and online education. Another potentially useful way for patients to self-manage LBP…

Abstract Information from individual classification systems or clinical prediction rules that aim to facilitate stratified care in low back pain is important but often not comprehensive enough to be used…