Psoriatic Arthritis
Psoriatic Arthritis Petros Efthimiou Joseph A. Markenson KEY POINTS Psoriatic arthritis (PsA) is a chronic inflammatory arthropathy of the peripheral joints and axial skeleton, occurring in a subset of patients…
Arthritis Associated with Ulcerative Colitis and Crohn’s Disease
Arthritis Associated with Ulcerative Colitis and Crohn’s Disease Kyriakos A. Kirou Allan Gibofsky KEY POINTS Intestinal inflammation is closely linked to the spondyloarthropathies (SpA). Among extraintestinal manifestations of inflammatory bowel…
The Vasculitides
The Vasculitides Yusuf Yazici Michael D. Lockshin KEY POINTS The major ischemic manifestations of vasculitides are defined by the type and size of the blood vessels involved and the tissue…
Ankylosing Spondylitis
Ankylosing Spondylitis Eric S. Schned KEY POINTS The diagnosis of ankylosing spondylitis (AS) should be strongly considered if four or more of the following clinical features are present: age of…
Pregnancy and Connective Tissue Disorders
Pregnancy and Connective Tissue Disorders Doruk Erkan Lisa R. Sammaritano KEY POINTS Pregnancy-induced physiologic changes and the complications in pregnancy may make assessment of connective tissue disorder (CTD) activity during…
Childhood Rheumatic Diseases
Childhood Rheumatic Diseases Thomas J. A. Lehman The rheumatic diseases of childhood represent a diverse group, both clinically and immunologically. Their etiologies are varied and their pathogeneses are unclear. Lyme…
Polymyalgia Rheumatica and Giant Cell Arteritis
Polymyalgia Rheumatica and Giant Cell Arteritis Richard Stern KEY POINTS Polymyalgia Rheumatica (PMR) PMR is a common illness in individuals older than 60 years and is manifested by proximal arthralgia/myalgia,…
Systemic Sclerosis and Related Syndromes
Systemic Sclerosis and Related Syndromes Robert F. Spiera KEY POINTS Scleroderma is a systemic fibrosing disease in which underlying vasculopathy plays a major role. Raynaud’s phenomenon is nearly ubiquitous in…
Sjögren’s Syndrome
Sjögren’s Syndrome Stuart S. Kassan KEY POINTS Sjögren’s syndrome (SS) is a common autoimmune disease that may occur alone or in combination with any of the other autoimmune diseases such…
Antiphospholipid Syndrome
Antiphospholipid Syndrome Doruk Erkan Lisa R. Sammaritano KEY POINTS The origin of antiphospholipid (aPL) antibodies is unknown but is hypothesized to be an incidental exposure to environmental agents inducing aPL…
