Total hip and knee arthroplasty is associated with significant perioperative pain, which can adversely affect recovery by increasing risk of complications, length of stay, and cost. Historically, opioids were the…
Multimodal pain management has become the standard of care following total hip and knee replacement. The advantages include decreasing opioid consumption and its associated side effects, facilitating earlier mobilization, and…
There have been multiple successful efforts to improve and shorten the recovery period after elective total joint arthroplasty. The development of rapid recovery protocols through a multidisciplinary approach has occurred…
Patient satisfaction and outcomes are increasingly influencing reimbursement, and multiple studies have shown a direct correlation between increased pain and decreased patient satisfaction. The current focus on opioid overuse has…
www.orthopedic.theclinics.com Perioperative Pain Management October 2017 • Volume 48 • Number 4 Editor-in-Chief FREDERICK M. AZAR Editorial Board CLAYTON C. BETTIN JAMES H. CALANDRUCCIO BENJAMIN J. GREAR BENJAMIN M. MAUCK…
Vascular manifestations associated with systemic lupus erythematosus (SLE) span a broad range, including vasculopathy. An understudied pathway of this morbidity is a repair component. Recent studies have elevated the anti-injury…
The recent appreciation that a subset of anti-DNA antibodies cross-reacts with the N -methyl-d-aspartate receptor encourages a renewed examination of antibrain reactivity in systemic lupus erythematosus (SLE) autoantibodies. Moreover, investigations…
The long history of elevated interferon (IFN)-α in association with disease activity in patients who have systemic lupus erythematosus (SLE) has assumed high significance in the past decade, with accumulating…
Systemic lupus erythematosus is arguably the most clinically and serologically diverse autoimmune disease. This article highlights the biomarkers helpful in diagnosing this disease. The authors’ own research is presented. Systemic…
Biomarkers have the potential to be useful tools for noninvasively evaluating and managing patients with lupus nephritis. Many candidate biomarkers have been identified, but they require validation in larger cohorts….
