Pregnancy and rheumatoid arthritis
Abstract Fertility is impaired in female patients with rheumatoid arthritis (RA), which is related to disease activity and the use of certain medication. During pregnancy, disease activity usually improves, but…
Monitoring in established RA: Role of imaging and soluble biomarkers
Abstract Rheumatoid arthritis (RA) disease activity often remains difficult to define and to quantify. As a result, numerous techniques to estimate clinical activity have been developed and are in clinical…
How does established rheumatoid arthritis develop, and are there possibilities for prevention?
Abstract Established rheumatoid arthritis (RA) is a chronic state with more or less joint damage and inflammation, which persists after a phase of early arthritis. Autoimmunity is the main determinant…
Treating to target in established rheumatoid arthritis: Challenges and opportunities in an era of novel targeted therapies and biosimilars
Abstract There is increasing consensus that periodic monitoring of disease activity status in rheumatoid arthritis (RA) patients to achieve and maintain remission, or at least low disease activity (LDA), the…
New therapeutic avenues in SLE
Abstract Although the use of corticosteroids and immunosuppressive agents such as cyclophosphamide and mycophenolate has led to reduced mortality in systemic lupus erythematosus (SLE), there is a need for development…
Corrigendum to “Risk of infection with biologic antirheumatic therapies in patients with rheumatoid arthritis” [Best Pract Res Clin Rheumatol 29 (2) (2015) 290–305]
The authors regret that the following sentence on page 300 is inaccurate due to incorrect citations, “There is a suggestion, from the results presented in the primary studies, that the…
Inflammatory myopathies and overlap syndromes: Update on histological and serological profile
Abstract The term ‘inflammatory myopathies’ (IMs) comprise a group of muscle diseases formed by four main categories known as polymyositis (PM), dermatomyositis (DM), inclusion body myositis (IBM) and immune-mediated necrotizing…
New biological therapies in Sjögren’s syndrome
Abstract Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by dryness and systemic involvement in more than a third of the patients. Patient management has suffered from the…
Lipid mediators of inflammation in rheumatoid arthritis and osteoarthritis
Abstract Rheumatoid arthritis (RA) and osteoarthritis (OA) are inflammatory joint diseases, characterized by pain and structural damage. Besides prostaglandins, usually targeted by non-steroidal anti-inflammatory drugs, other lipids, including fatty acids,…
Metabolomics to identify biomarkers and as a predictive tool in inflammatory diseases
Abstract There is an overwhelming need for a simple, reliable tool that aids clinicians in diagnosing, assessing disease activity and treating rheumatic conditions. Identification of biomarkers in partially understood inflammatory…
