Dupuytren Disease
Dupuytren disease (DD) is the most common heritable disorder affecting connective tissues. It is an inherited, benign, chronic progressive condition that results in fibrotic changes of the palmar and digital…
Chronic Infections
Acknowledgment: Govind Narain Malaviya was the main contributor to the section on leprosy. He was a leader in surgery for Hansen disease in the world and has now retired. I…
Anesthesia
Acknowledgments: The author wishes to recognize the work of previous authors Drs. Lauren Fisher and Michael Gordon for their contributions to Green’s Operative Hand Surgery and to this manuscript. There…
Acute Infections of the Hand
General Principles Hippocrates’ principles for the treatment of hand infections are fundamentally valid today. Wounds were kept clean with frequent changes of wine-soaked dressings. Dressings were kept loose “so as…
Why is osteoarthritis an age-related disease?
Although older age is the greatest risk factor for osteoarthritis (OA), OA is not an inevitable consequence of growing old. Radiographic changes of OA, particularly osteophytes, are common in the…
Developing a minimum standard of care for treating people with osteoarthritis of the hip and knee
We reviewed three recently published guidelines for the management of osteoarthritis (OA) and considered the evidence and potential for implementation. From this we propose a minimum standard of care, or…
Targeted therapies in osteoarthritis: a systematic review of the trials on www.clinicaltrials.gov
A systematic review of the clinical trials in osteoarthritis registered on the public website of the Clinical Trials Data Bank at the National Institutes of Health (NIH) has been performed….
Non-pharmacological approaches for the treatment of osteoarthritis
For the most part, non-pharmacological approaches are recommended for osteoarthritis treatment. This recommendation is based mainly on biomechanical observations leading to a modulation of the symptomatic loading joint. Approaches include…
Targeting the synovial tissue for treating osteoarthritis (OA): where is the evidence?
Osteoarthritis (OA) is often a progressive and disabling disease, which occurs in the setting of a variety of risk factors – such as advancing age, obesity and trauma – that…
What are the best markers for disease progression in osteoarthritis (OA)?
To be able to prevent progression of osteoarthritis, the knowledge of prognostic factors of this progression is important. If certain prognostic factors are modifiable, they may enhance our ability to…
