The mirabilis period of autoimmunity
The development of autoimmunity and autoimmune diseases is believed to involve interactions between genes, hormones and the environment and was labelled in 1989 as ‘the mosaic of autoimmunity’. This complex…
High-energy trauma
Burdens and trends Injury/trauma from all causes kills 5.8 million per year globally, accounting for 10% of the world’s deaths. This is 32% more than the number of deaths from…
Advancements in the Management of Spine Disorders
Spinal disorders and especially back and neck pain affect more people and have greater impact on work capacity and health-care costs than any other musculoskeletal condition. One of the difficulties…
Advances in the treatment of inflammatory arthritis
The inflammatory arthritides are a diverse group of conditions characterised by joint inflammation which can lead to pain, deformity and disability. Of these diseases, rheumatoid arthritis (RA) and spondyloarthritis are…
Improving musculoskeletal health: Global issues
Musculoskeletal (MSK) disorders are among the leading reasons why patients consult a family or primary health practitioner, take time off work and become disabled. Many of the MSK disorders are…
The need to address the burden of musculoskeletal conditions
Musculoskeletal conditions are common in men and women of all ages across all socio-demographic strata of society. They are the most common cause of severe long-term pain and physical disability…
Taking advances from bench to bedside during the last decade
The remarkable advances in understanding the pathogenesis and therapeutic options for rheumatoid arthritis over the last 10 years are a leap forward in the treatment of this disease. This has…
Achievements during the Bone and Joint Decade 2000–2010
Musculoskeletal diseases continue to produce major disability around the world. Advances in therapy – particularly for the inflammatory diseases – have the potential to eradicate the inflammation and thus prevent…
Looking back at the start of the bone and joint decade what have we learnt?
The Bone and Joint Decade 2000–2010 started as a Swedish initiative in 1996 leading to the UN declaration 1999 followed by the WHO launch 2000. A ten year multidisciplinary and…
Gait deviations in individuals with inflammatory joint diseases and osteoarthritis and the usage of three-dimensional gait analysis
This chapter describes three-dimensional gait analysis and common gait deviations in adults with rheumatoid arthritis (RA) and osteoarthritis (OA). Furthermore, we describe changes in gait deviations following surgical and non-surgical…
