Schwannoma (Neurilemmoma) and Neurofibroma CLINICAL SUMMARY Schwannomas and neurofibromas are slow-growing, benign nerve sheath tumors that arise either eccentrically from peripheral myelin-producing cells or centrally from intraneural support cells, respectively….
Malignant Fibrous Histiocytoma, High-Grade Pleomorphic Undifferentiated Sarcoma CLINICAL SUMMARY Undifferentiated sarcoma is the preferred term for the previously named malignant fibrous histiocytoma (MFH). This designation probably encompasses a common endpoint…
Diffuse Pigmented Villonodular Synovitis (PVNS) CLINICAL SUMMARY Diffuse PVNS is a benign, proliferative disorder of the synovium with a distinctive complex nodular appearance on MRI. It is most common in…
History Age, Pain AGE The patient’s age and clinical presentation are very helpful in predicting the diagnosis in musculoskeletal tumors and greatly aid in the interpretation of the imaging studies….
Extraabdominal Desmoid Tumor, Aggressive Fibromatosis CLINICAL SUMMARY Fibromatosis is a benign, locally aggressive tumor originating in an intermuscular location, with a highly infiltrative growth pattern and a propensity to recur…
Tenosynovial Pigmented Villonodular Synovitis (PVNS), Nodular PVNS CLINICAL SUMMARY Giant cell tumor of tendon sheath is a slow-growing tumor associated with mechanical pain, most commonly in the hands and feet….
Congenital Venous Malformation, Intramuscular Hemangioma, Low-Flow Vascular Malformation CLINICAL SUMMARY Congenital vascular malformations can be found in any organ. Intramuscular lesions, often described as intramuscular hemangiomas , are easily recognized…
CLINICAL SUMMARY Synovial sarcoma is the fourth or fifth most common subtype of soft tissue sarcoma and is distinguished by its younger age of presentation, frequent history of pain, and…
CLINICAL SUMMARY Multiple myeloma presents as a proliferation of plasma cells in the marrow and is the most common primary malignancy of bone. Like other round cell tumors, myeloma lesions…
