37 Fluid Flow and Strain in Bone
10.1055/b-0035-122037 37 Fluid Flow and Strain in Bone Petra Juffer, Astrid D. Bakker, Richard T. Jaspers, and Jenneke Klein-Nulend It has been well established that lack of physical exercise leads…
54 How to Limit Bias in Experimental Research
10.1055/b-0035-122054 54 How to Limit Bias in Experimental Research Paul J. Jenkins All scientific studies are subject to experimental error, and it is the duty of the investigator to eliminate…
52 Power and Sample Size Calculation
10.1055/b-0035-122052 52 Power and Sample Size Calculation Nan van Geloven, Rob de Haan, Marcel Dijkgraaf, Michael Tanck, Johannes B. Reitsma 52.1 Why Perform a Sample Size Calculation Prior to a…
38 Biomechanics of Bone Cells
10.1055/b-0035-122038 38 Biomechanics of Bone Cells Janak L. Pathak, Ineke D.C. Jansen, Nathalie Bravenboer, Jenneke Klein-Nulend, and Astrid D. Bakker Mechanosensitive bone cells translate mechanical stimuli into a biological response….
51 Study Design
10.1055/b-0035-122051 51 Study Design Taco Johan Blokhuis Study design in experimental research is fundamentally different from study design in clinical research for several reasons. First, the question to be answered…
48 Use of Growth Factors in Musculoskeletal Research
10.1055/b-0035-122048 48 Use of Growth Factors in Musculoskeletal Research Iain R. Murray Growth factors (GFs) are naturally occurring substances that bind to receptors on the cell surface and are capable…
50 Biological Evaluation and Testing of Medical Devices
10.1055/b-0035-122050 50 Biological Evaluation and Testing of Medical Devices Dieter R. Dannhorn In order to exclude potential biological hazards or to control residual risks as much as possible, the consolidated…
34 Image Analysis Histomorphometry Stereology
10.1055/b-0035-122034 34 Image Analysis Histomorphometry Stereology Chuanyong Lu, Ralph Marcucio, and Theodore Miclau Jargon Simplified: Stereology Stereology is a method to get unbiased quantitative estimation of the first-order stereological parameters…
27 Ultrasound Techniques for Imaging Bone
10.1055/b-0035-122027 27 Ultrasound Techniques for Imaging Bone Thomas J. MacGillivray and Erin Ross Fracture recovery is currently assessed using a combination of physical assessment and X-ray. 1 The limitations of…
45 In Vivo Models for Articular Cartilage Repair
10.1055/b-0035-122045 45 In Vivo Models for Articular Cartilage Repair Paul Hindle The translation of basic science research requires rigorous investigation prior to human clinical trials. An important step in this…
