46 In Vivo Soft Tissue Models
10.1055/b-0035-122046 46 In Vivo Soft Tissue Models Melanie Jean Coathup, Catherine Jane Pendegrass, Allen Edward Goodship, and Gordon William Blunn This chapter describes the use of a plethora of different…
44 In Vivo Models for Bone and Joint Infections
10.1055/b-0035-122044 44 In Vivo Models for Bone and Joint Infections Volker Alt, Christoph Henkenberens, and Reinhard Schnettler Bone and joint infections do not represent a uniform disease, but a heterogeneous…
40 Genetically Modified Models for Bone Repair
10.1055/b-0035-122040 40 Genetically Modified Models for Bone Repair Rana Abou-Khalil and Céline Colnot Delayed fracture repair and nonunions represent a major clinical challenge due to the lack of understanding of…
45 In Vivo Models for Articular Cartilage Repair
10.1055/b-0035-122045 45 In Vivo Models for Articular Cartilage Repair Paul Hindle The translation of basic science research requires rigorous investigation prior to human clinical trials. An important step in this…
43 Models for Impaired Healing
10.1055/b-0035-122043 43 Models for Impaired Healing Joseph Borrelli, Jr. Fracture healing occurs by one of two well-described ways. Direct fracture healing, which is believed to be uncommon in nature, involves…
36 Cartilage Explants and Organ Culture Models
10.1055/b-0035-122036 36 Cartilage Explants and Organ Culture Models Innes D.M. Smith Cartilage is a unique tissue that allows the frictionless motion of a joint while withstanding considerable forces. Unfortunately, for…
28 In Vivo Scanning
10.1055/b-0035-122028 28 In Vivo Scanning Scott Ian Kay Semple Magnetic resonance imaging (MRI) is an ideal tool for investigation of the musculoskeletal system and of cartilage in particular. Since MRI…
29 Imaging of Cartilage Function
10.1055/b-0035-122029 29 Imaging of Cartilage Function Gabby B. Joseph and Thomas M. Link Osteoarthritis (OA) is a degenerative joint disease affecting more than 27 million people in the United States…
42 Animal Models for Bone Healing
10.1055/b-0035-122042 42 Animal Models for Bone Healing Hamish Simpson and Leanora Anne Mills An experimental model for studying bone repair needs to reflect the biomechanics and the physiology of the…
41 General Considerations for an In Vivo Model
10.1055/b-0035-122041 41 General Considerations for an In Vivo Model Leanora Anne Mills and Hamish Simpson The American National Research Council Committee on Animal Models for Research and Aging drafted the…
