5 Osteomyelitis
Martin McNally Osteomyelitis is a fascinating condition that can affect all parts of the human skeleton. It presents in several distinct ways, but all have varying degrees of inflammation,…
8 Infection after Fracture Fixation and Infected Nonunions
Arvind von Keudell and Michael J. Weaver Infection after fracture surgery is a challenging entity. Prompt diagnosis and treatment is of paramount importance. Successful treatment includes culture-specific antibiotic therapy…
7 Management of Periprosthetic Joint Infection
Malcolm E. Dombrowski and Brian A. Klatt Periprosthetic joint infection (PJI) continues to be a devastating problem in the field of total joint arthroplasty. There are a number of…
6 Treatment of the Septic Native Joint
Timothy L. Tan and Sommer Hammoud A septic native joint can be a debilitating condition that is associated with significant morbidity and mortality. Traditionally, a septic native joint was…
4 Surgical Wound Dressings after Treating Orthopaedic Infections
Patrick Moody and Bryan Springer The postoperative dressing functions as an important barrier to prevent orthopaedic infections and reinfections. Preoperative assessment of patient factors and intraoperative evaluation of the…
3 Irrigation Solutions for Orthopaedic Infections
Michael Yayac, Samuel J. Clarkson, Craig Della Valle, and Javad Parvizi This chapter will provide an overview of antiseptic agents used to irrigate wounds for the prevention or treatment…
2 Antibiotics for Orthopaedic Infections
Alaina S. Ritter and Sandra B. Nelson Antibiotics play a critical role in the treatment of bone and joint infections. In clinical practice, antibiotics may be delivered intravenously, orally,…
1 Detection of Microbes in Orthopaedic Infections
Michael Henry, Andy O. Miller, and Barry D. Brause A very broad range of microorganisms cause orthopaedic infections. Modern diagnosis depends on traditional culture techniques, which remain in common…
Board review questions
Chapter 1 : History of pediatric critical care medicine 1. Treatment for which of the following disease entities was not an important trigger in the early development of distinct, full-time,…
Hemoglobinopathies
• The pathophysiology of sickle cell disease is multifactorial, involving hemoglobin polymerization, oxidative damage to cell membrane proteins, white blood cell activation and inflammation, activation of the clotting cascade, and…
