Newer Immunosuppressants for Rheumatologic Disease

May 20, 2025 by in RHEUMATOLOGY Comments Off on Newer Immunosuppressants for Rheumatologic Disease

With the advent of small-molecule immune modulators, recombinant fusion proteins, and monoclonal antibodies, treatment options for patients with rheumatic diseases are now broad. These agents carry significant risks and an…

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Gut and Joint Microbiomes

May 20, 2025 by in RHEUMATOLOGY Comments Off on Gut and Joint Microbiomes

This review summarizes and discusses key recent findings suggesting that microbiomes can play a role in the development and progression of osteoarthritis. Evidence supporting a gut microbiome-joint connection derived from…

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Animal Models Informing the Role of the Microbiome and its Metabolites in Rheumatoid Arthritis

May 20, 2025 by in RHEUMATOLOGY Comments Off on Animal Models Informing the Role of the Microbiome and its Metabolites in Rheumatoid Arthritis

Animal models of rheumatoid arthritis (RA) are essential for understanding the disease’s mechanisms and developing new treatments. Recent research highlights the microbiome’s significant roles in RA pathogenesis, influencing disease susceptibility…

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It Takes a Village

May 20, 2025 by in RHEUMATOLOGY Comments Off on It Takes a Village

Multiple risk factors for juvenile idiopathic arthritis (JIA) influence the microbiome, and various differences in the oral and fecal microbiome have been described to date in JIA. This review summarizes…

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