10.1055/b-0035-122040 40 Genetically Modified Models for Bone Repair Rana Abou-Khalil and Céline Colnot Delayed fracture repair and nonunions represent a major clinical challenge due to the lack of understanding of…
10.1055/b-0035-122045 45 In Vivo Models for Articular Cartilage Repair Paul Hindle The translation of basic science research requires rigorous investigation prior to human clinical trials. An important step in this…
10.1055/b-0035-122043 43 Models for Impaired Healing Joseph Borrelli, Jr. Fracture healing occurs by one of two well-described ways. Direct fracture healing, which is believed to be uncommon in nature, involves…
10.1055/b-0035-122036 36 Cartilage Explants and Organ Culture Models Innes D.M. Smith Cartilage is a unique tissue that allows the frictionless motion of a joint while withstanding considerable forces. Unfortunately, for…
10.1055/b-0035-122028 28 In Vivo Scanning Scott Ian Kay Semple Magnetic resonance imaging (MRI) is an ideal tool for investigation of the musculoskeletal system and of cartilage in particular. Since MRI…
10.1055/b-0035-122029 29 Imaging of Cartilage Function Gabby B. Joseph and Thomas M. Link Osteoarthritis (OA) is a degenerative joint disease affecting more than 27 million people in the United States…
10.1055/b-0035-122042 42 Animal Models for Bone Healing Hamish Simpson and Leanora Anne Mills An experimental model for studying bone repair needs to reflect the biomechanics and the physiology of the…
10.1055/b-0035-122041 41 General Considerations for an In Vivo Model Leanora Anne Mills and Hamish Simpson The American National Research Council Committee on Animal Models for Research and Aging drafted the…
10.1055/b-0035-122035 35 Cell Culture Research Franz Jakob, Barbara Klotz, Birgit Mentrup, Torsten Blunk, Andre F. Steinert, and Regina Ebert Musculoskeletal diseases are increasingly important in all age groups with respect…
10.1055/b-0035-122031 31 Immunohistochemistry Wing-Hoi Cheung and Simon Kwoon Ho Chow The word “immunohistochemistry” (IHC) is composed of “immuno-,” “histo-,” and “chemistry,” which refer to the application of immunological techniques to…
