The pathologic correlates of interstitial lung disease (ILD) secondary to connective tissue disease (CTD) comprise a diverse group of histologic patterns. Lung biopsies in patients with CTD-associated ILD tend to…
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA www.rheumatic.theclinics.com Consulting Editor MICHAEL H. WEISMAN May 2015 • Volume 41 • Number 2
Aryeh Fischer, MD, Editor Paul F. Dellaripa, MD, Editor This issue of Rheumatic Disease Clinics of North America is dedicated to Lung Disease in Rheumatic Diseases and aims to provide…
Michael H. Weisman, MD, Consulting Editor Aryeh and Paul have created a unique volume that should be a reference standard for years to come regarding disease description, pathogenesis, and treatment…
Patients with systemic sclerosis (SSc; also called scleroderma) have to cope with not only the physical impacts of the disease but also the emotional and social consequences of living with…
Systemic sclerosis (SSc; scleroderma) is a chronic autoimmune connective tissue disease characterized by microvascular obliteration and sclerosis of the skin and internal organs. Although the clinical hallmark of the disease…
Pulmonary arterial hypertension (PAH) is one of the leading causes of death in patients with systemic sclerosis (SSc). Given the high prevalence and poor survival of SSc-PAH, and that aggressive…
Scleroderma renal crisis is a rare complication of systemic sclerosis (SSc) that remains severe. Prompt recognition and initiation of therapy with an angiotensin-converting-enzyme inhibitor offer the best chance to achieve…
The gastrointestinal tract, affecting more than 90% of patients, is the internal organ most frequently involved in systemic sclerosis. Any part of the gastrointestinal tract can be affected, from the…
Although scleroderma-associated interstitial lung disease (SSc-ILD) is a significant contributor to both morbidity and mortality, its pathogenesis is largely unclear. Pulmonary function tests and high-resolution computed tomographic scanning continue to…
