We compiled information on antibodies in Sjögren syndrome, focusing more on clinical manifestations associated with anti-Ro/SSA and anti-La/SSB antibodies and studies regarding novel antibodies. We reviewed previous as well as…
The management of patients suffering from primary Sjögren syndrome (pSS) has long been mainly symptomatic and demonstration of effectiveness of systemic drugs was lacking. However, progress made in the understanding…
R. Hal Scofield, MD, Editor Sjögren syndrome is a chronic, systemic autoimmune disease that is common and has important life-altering and severe effects on those with the disease. Despite these facts, the…
Michael H. Weisman, MD, Consulting Editor Hal Scofield has done a remarkable job in assembling a timely, up-to-date, and thoughtful review of Sjogren syndrome (SS). It does appear that the…
Diagnostic imaging plays a crucial role in confirming the diagnosis of musculoskeletal (MSK) infection and determining the severity and extent of disease. The clinical diagnosis may be challenging due to…
The clinical diagnosis of synovial tumors and synovial proliferative processes is difficult, as symptoms and physical examination findings are often nonspecific. Advanced imaging modalities, such as MRI, high-resolution ultrasound, and…
Various imaging modalities, including color duplex ultrasonography, CT angiography, magnetic resonance angiography, and PET, are emerging as important aids to the diagnosis, staging, evaluation of disease activity and response to…
Systemic rheumatic diseases frequently pose diagnostic challenges to the clinician. The precise nature of the disorder can be obscure and different disorders can present with similar symptoms, such as joint…
Multifocal osteomyelitis and synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome constitute a spectrum of disease that includes inflammatory bone lesions and dermatologic findings. Radiographic features resemble those of the…
Inflammatory and chronic structural changes are objective signs of axial spondyloarthritis. In the sacroiliac joints (SIJs), inflammation (sacroiliitis) can be visualized as bone marrow edema, whereas chronic structural changes are…
