The Epidemiology of Psoriatic Arthritis
Psoriatic arthritis (PsA) is a chronic systemic inflammatory disorder characterized by joint and entheseal inflammation with a prevalence of 0.05% to 0.25% of the population and 6% to 41% of…
Psoriatic Arthritis
Christopher T. Ritchlin, MD, MPH, Editor It is hard to believe that little more than 40 years have elapsed since psoriatic arthritis was first described as a separate entity, HLAB27…
Psoriatic Arthritis
Michael H. Weisman, MD, Consulting Editor Chris Ritchlin has done a remarkable job assembling the expertise necessary to put together a timely comprehensive review of Psoriatic Arthritis. We learn how…
Glucocorticoid-induced Osteoporosis
Glucocorticoid-induced osteoporosis (GIOP) is one of the most common and serious adverse effects associated with glucocorticoid use. This article highlights GIOP pathophysiology, epidemiologic associations, effective treatment, and lifestyle modifications that…
Infection Risk and Safety of Corticosteroid Use
Corticosteroids are frequently used to treat rheumatic diseases. Their use comes with several well-established risks, including osteoporosis, avascular necrosis, glaucoma, and diabetes. The risk of infection is of utmost concern…
Corticosteroids in Sarcoidosis
Corticosteroids are the drug of choice for the treatment of sarcoidosis. Because the natural course of sarcoidosis may be self-limiting and/or cause no long-term harm, treatment is not mandatory. Corticosteroids…
Corticosteroids in Myositis and Scleroderma
Idiopathic inflammatory myopathies (IIMs) involve inflammation of the muscles and are classified by the patterns of presentation and immunohistopathologic features on skin and muscle biopsy into 4 categories: dermatomyositis, polymyositis,…
Corticosteroids for Pain of Spinal Origin
Targeted interventional delivery of corticosteroids remains a mainstay of treatment for spinal pain syndromes because this approach has a wider therapeutic index than other approaches. The best evidence for analgesic…
Corticosteroids in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis
Glucocorticoids (GCs) have been the cornerstone of antineutrophil cytoplasmic antibody–associated vasculitis (AAV) therapy since their advent in the 1950s. There is considerable variation in their use, both with respect to…
Glucocorticoids for Management of Polymyalgia Rheumatica and Giant Cell Arteritis
Diagnosis of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) is based on typical clinical, histologic, and laboratory features. Ultrasonographic imaging in PMR with assessment especially of subdeltoid bursitis can…
