Chapter 7 Upon successful completion of this chapter, the student will be able to: • Provide an understanding of the essential importance of using the seven rights and three befores in administering IV medications. • Provide the needed information that will assist in ensuring that quality patient safety is provided during IV therapy. • Ensure that the pharmacokinetics (absorption, distribution, metabolism, and excretion) of medications in general and the rapidity of these processes with IV infusions are understood. • Review basic drugs used for IV therapy by drug classification and the body system that is most frequently affected. • Furnish the basic information of drug compatibilities and incompatibilities including listing those medications that are incompatible with basic IV fluids. • Convey the basic information to provide patient safety during the administration of medications using IV infusion. uptake of medications into the body through or across tissues. medication that binds to the receptor site and stimulates the function of that site; a drug that mimics a function of the body. medication that binds to the receptor site to prevent other medications from binding to those sites; cancellation or reduction of one drug’s effect by another drug. pertaining to the destruction of bacteria; drugs or chemicals that can destroy bacteria. inhibiting or retarding growth of bacteria; drugs or chemicals that can inhibit or retard growth of bacteria. an uninterrupted injection of a liquid substance into the vein. dispersion of medication particles to sites in the body. elimination of a medication from the body. to escape from the vessel into the tissue. unexpected, unusual response to a drug. administration of medications or an infusion that is not continuous but is interrupted between doses. the use of a needle attached to a syringe to instill a single dose of medication into a vein. physical or chemical processes in the body that inactivate a drug for excretion; biotransformation. older term for a controlled drug that depresses the central nervous system to relieve pain and has the potential to cause habituation or addiction. drug containing or derived from opium. drug that is a synthetic analgesic with the strength of a morphine-like substance but is not derived from opium. patient controlled analgesia (PCA) a controlled infusion that allows the patient to administer a predetermined amount of analgesic. peripheral parenteral nutrition (PPN) method of administering diluted nutritional substances in a peripheral IV site. processing of drugs in the body. new infection that appears during the course of treatment for a primary infection. total parenteral nutrition (TPN) providing nutritional support through a central IV route. As with all administration of medications, the professional responsible for the intravenous infusion also has many responsibilities other than just starting the infusion. As discussed in Chapter 5, the calculation of the accurate dose and dosage is most important because medications that have been given intravenously cannot be retrieved. The patient assessment prior to infusion is important so that any changes in the patient’s condition can be evaluated based on correct and current information. The importance of understanding the pharmacology of a medication prior to administration cannot be stressed enough.
Pharmacology Related to Intravenous Therapy