© Springer International Publishing Switzerland 2016
Piero Volpi (ed.)Arthroscopy and Sport Injuries10.1007/978-3-319-14815-1_4848. Management of Anterior Cruciate Ligament Lesion in Adolescents
(1)
Unità Operativa di Chirurgia del Ginocchio e Traumatologia dello Sport, Istituto Clinico Humanitas, Via Manzoni 56, Rozzano, Milano, 20089, Italy
(2)
Knee Orthopedics and Sport Traumatology Unit, Humanitas Clinical Institute IRCCS, Milan, Italy
(3)
Head of Medical Staff FC Internazionale Milan, Milan, Italy
Keywords
ACL tearAdolescentManagementPediatricAnterior cruciate ligament (ACL) lesions in adolescents represent a serious concern for the physician. The increased involvement of children and adolescents in organized sports beginning at an early age raises concern regarding risk and severity of sports injury. Inevitably with increased participation and training come an increasing number of sports injuries. Three types of youth sports injury, anterior cruciate ligament (ACL) injury, concussion, and physeal injury, are the focus of much recent media and scholarly attention given their frequency, potential for adverse long-term health outcomes, and escalating healthcare costs [1]. If not managed appropriately, they can also lead to long-term complications which could negatively affect ability to continue to participate in exercise and sports as well as threaten general health. Management of ACL injuries is an area of controversy because it can affect long-term growth and recovery as well as the ability to participate in sports. No well-designed epidemiologic studies to document ACL injury rates have been conducted in children younger than 14 years. Although there have been reports of sports-related ACL injuries in children as young as 5 years, the limited data available suggest that ACL disruptions in children younger than 12 years are rare [2]. In 1988, McCarroll et al. [3] found that of the 1,722 ACL injuries diagnosed over a 6-year period at their sports medicine center, 3 % were in children 14 years and younger; the authors conclude that a conservative approach, although reasonable, has not always been feasible in the young population who has a strong desire to pursue competitive athletics. The Norwegian ACL surgical registry collects data for all ACL surgeries performed at participating institutions nationwide. From 2004 to 2011, this registry recorded a total of only 8–9 ACL surgeries each year for children 11–13 years of age. This represents a small fraction (0.6 %) of the total number of ACL surgeries recorded each year (1,441) in this registry across all age groups. For the children who had surgery, the age at the time of injury ranged from 9 to 13 years. The ACL surgery rate for 12- to 13-year-olds (3.5 per 100,000 citizens) was substantially lower than that for 16- to 39-year-olds (85 surgeries per 100,000 citizens), the age group at highest risk [4]. Again, these numbers underestimate the actual injury rates, because they do not account for those treated nonoperatively. ACL injury risk begins to increase significantly at 12–13 years of age in girls and at 14–15 years of age in boys. Female athletes between 15 and 20 years of age account for the largest numbers of ACL injuries reported. The gender disparity in ACL injury rates among athletes begins to appear around the time of the growth spurt (12–14 years of age for girls and 14–16 years of age for boys), peaks during adolescence, and declines in early adulthood [5]. At the high school level, ACL injury rates in gender-comparable sports (soccer, basketball, baseball/softball, track, volleyball) are 2.5–6.2 times higher in girls compared with boys [6]. In college athletics, ACL injury rates are 2.4–4.1 times higher for women, and at the professional level, ACL injury rates for men and women are essentially equal [7]. The young athlete may be particularly vulnerable to sports injury because of the physical and physiological processes of growth; moreover, young athletes might also be at increased risk of injury because of immature or underdeveloped coordination, skills, and perception. Although ACL injuries account for approximately 3 % of all injuries in college sports, they account for 88 % of injuries associated with 10 or more days of time lost from sports participation. An ACL injury at an early age is a life-changing event. In addition to surgery and many months of rehabilitation, the treatment costs can be substantial ($17,000–$25,000 per injury), and the time lost from school and sports participation can have considerable effects on the athlete’s mental health and academic performance [8]. Beyond these more immediate effects, an ACL injury also has long-term health consequences. Regardless of the type of treatment, athletes with ACL injury are up to ten times more likely to develop early-onset degenerative knee osteoarthritis, a condition that not only limits one’s ability to participate in sports but also often leads to chronic pain and disability. A systematic review of a series of long-term studies suggests that the rates of degenerative knee osteoarthritis 10–20 years after ACL injury are more than 50 % [9]. This means children and teenagers who suffer ACL injuries are likely to face chronic pain and functional limitations from knee osteoarthritis in their 20s and 30s.
48.1 Risk Factors
ACL injury risk in young athletes is probably multifactorial. Injury data from many fields demonstrate that numerous physical and psychological parameters affect ACL injury rates. Although ACL injury rates increase with age in both genders, girls have higher rates immediately after the growth spurt. It is likely that the increases in body weight, height, and bone length during pubertal development underlie the mechanism of increased risk of ACL injury with increasing age. During puberty, the tibia and femur grow at a rapid rate. This growth of the two longest levers in the human body translates into greater torques on the knee. In pubertal boys, testosterone mediates significant increases in muscular power, strength, and coordination, which affords them with greater neuromuscular control of these larger body dimensions. Pubertal girls do not experience this same growth spurt in muscular power, strength, and coordination, which likely explains their higher rates of ACL injuries compared with pubertal boys; the preadolescent athletes show no gender differences in ACL injury rates [10, 11]. Hormonal factors are also likely to play a role; however, results of studies investigating hormonal factors are both equivocal and controversial. Although the female knee appears to get slightly more lax, on the order of 0.5 mm, at mid-menstrual cycle, injuries tend to cluster near the start of menses at the polar opposite time in the cycle [12]. Activation of the quadriceps before the hamstrings, a pattern more frequently seen in female individuals, increases the anterior shear force that directly loads the ACL and also could be related to increased dynamic valgus alignment at initial contact during cutting and landing maneuvers. Although fatigue is often cited as a potential risk factor for ACL injury, there are relatively few published studies to support or refute this [13, 14]; certainly a greater weight and BMI have been associated with increased risk of ACL injury. A narrow intercondylar notch, where the ACL is housed, is proposed to increase ACL injury risk, because a narrow notch tends to be associated with a smaller, weaker ACL and also could cause increased elongation of the ACL under high tension. Some studies have shown that a narrow notch increases risk of ACL injury; however, others have shown no association between notch width and ACL injury [15, 16]. Subtalar joint overpronation, flat foot, has been associated with noncontact ACL injuries, likely because overpronation increases anterior translation of the tibia with respect to the femur, thereby increasing the strain on the ACL [17]. Generalized joint laxity and knee hyperextension were found to significantly increase the risk for ACL injury in female soccer players. Patients with ACL injury have significantly more knee recurvatum at 10° and 90° of hip flexion and an increased ability to touch palms to the floor. Athletes with generalized joint laxity had a 2.7 times greater risk of ACL injury than did those without generalized laxity, and those with increased anteroposterior laxity of the knee, as measured by a knee arthrometer, had an approximately three times greater risk of ACL injury than did those without such laxity. Joint laxity affects not only sagittal knee motion (hyperextension) but also coronal knee motion (valgus), which can strain the ACL and be related to increased risk in athletes [18].
48.2 ACL Tear
The most common mechanism of ACL injury is a noncontact pivoting motion on a fixed foot or a trauma with the knee in hyperextension or rotation. If a hemarthrosis develops within a few hours after the trauma in the absence of a bony injury, there is a 70 % chance of ACL injury [19]. The examiner should assess gait and alignment and range of motion and assess the affected joint and compare it with the contralateral joint, taking into account that most children may have hyperlaxity which decreases with maturity. Radiographs should be examined for bony injuries. Magnetic resonance imaging (MRI) can be useful, but may be no better than accurate clinical examination. In a pediatric athlete with an acute traumatic knee effusion, the Lachman test, anterior drawer test, and pivot shift test are clinical examinations that aid in making the diagnosis of an ACL tear. The Lachman test is considered the most accurate of the three commonly performed clinical tests for an acute ACL tear, showing a pooled sensitivity of 85 % (95 % confidence interval CI) and a pooled specificity of 94 % (95 % CI 92–95). The pivot shift test is very specific, namely, 98 % (95 % CI), but has a poor sensitivity of 24 % (95 % CI 21–27). Lastly, the knee arthrometer is an objective, accurate, and validated tool that measures, in millimeters, the amount of tibial translation relative to the femur while performing a Lachman test and, thus, augments the clinical examination when examining a patient with an ACL tear [20].
48.3 Management of ACL Tear
The management of ACL deficiency in skeletally mature children is still controversial, especially in terms of operative timing and surgical technique. Conservative management is not recommended, as it is accompanied by marked reduction in activity, decline in functional performance, and development of early osteoarthritis. Historically, delayed anatomical ACL reconstructions were preferred [21] recommending extensive rehabilitation and return to activities with a brace to skeletal maturity and growth plate closure, to allow an anatomical adult-like reconstruction. The present trend favors early reconstruction, using either extra-physeal techniques in very young athletes or anatomical reconstruction techniques placing the tibial and femoral tunnels close to the center on the growth plate of the tibia and femur in young athletes closer to skeletal maturity [22]. An ACL tear in a child is not a surgical emergency; multiple timely discussions with the parents and the child about the appropriate management options and understanding their goals and expectations are very important. The general indications for surgery are the patient’s inability to participate in his or her chosen sport, instability that affects activities of daily living, and an associated repairable meniscal tear or a knee injury with multiple torn ligaments. Treatment of ACL injuries in the skeletally immature patient remains controversial, because standard ACL reconstructions involve the use of drill holes that cross the open physes and may potentially cause growth disturbance, such as shortening or angulation of the child’s leg. A meta-analysis of 55 studies suggested that the risk of leg length difference or angular leg deviations was approximately 2 % after ACL reconstruction in children and adolescents. The authors recommended randomized controlled trials to clarify this risk more accurately [23]. But ACL surgery is about 90 % successful in restoring knee stability and patient satisfaction. Ideally, surgical treatment of an ACL tear in a skeletally immature athlete would be postponed until skeletal maturity, and the athlete would not develop meniscal tears during that waiting time. Most recent literature now supports early surgery for pediatric athletes with an ACL-deficient knee and recurrent episodes of instability [24]. No consensus exists on the best method to treat an ACL tear in a pediatric athlete. Safe and effective surgical techniques continue to evolve. However, the current literature suggests reasonable, evidence-based management options that minimize the risks of iatrogenic growth plate injury [25, 26]. The two principal ACL surgery techniques performed on a pediatric athlete are physeal sparing or transphyseal and all inside.