Evidence-Based Treatments for Fractures Around the Knee Joint


Recommendations

Grade of recommendation

Distal femoral physeal injuries

Reduction and surgical fixation is indicated for all distal femoral physeal injuries

C

Surgical fixation is not associated with an increased risk of growth arrest

I

Transphyseal fixation does not increase the rate of growth arrest and deformity as compared with physeal sparing techniques

C

The risk of growth arrest increases with increasing Salter Harris classification

B

High energy injuries are associated with a higher risk of growth arrest

B

Anterior tibial spine fractures

All Type II injuries should be treated by surgical reduction and internal fixation

C

Open surgery is associated with fewer complications than arthroscopic surgery

C

Screw fixation is superior to suture fixation

C

The risk of complications increases with increasing Myers and McKeever classification

B

Transphyseal screw fixation is safe

B



Of the cases with patient level data (151 patients), Basener et al. reported a 27 % rate of growth arrest in patients treated with surgical fixation, compared to 37 % with no surgical fixation. The surgical fixation group consisted of only 30 patients compared to 121 in the non-surgical fixation group, which may have contributed to the lower reported prevalence in the former group. This is supported by the overall incidence of growth disturbance which was greater in patients who were not treated with surgical fixation (63 % vs. 58 %). Another possible confounding factor is the selection and treatment bias of the treating surgeon in fractures that are treated with surgical fixation.



Does Transphyseal Pinning Increase the Risk of Growth Arrest as Compared with Physeal Sparing Techniques?


Violating physeal plates with metalwork has always had a theoretical association with increased risk of growth arrest. Growth disturbances are a recognised sequlae of paediatric distal femoral injuries [8] and for this reason understanding the effects of metalwork around the physeal plate in these injuries is of paramount importance. Arkader et al. [5] demonstrated that fractures that were internally fixed with none physeal-sparing techniques (Steinman pins; n = 20) had a higher rate of complications (65 %) compared to physeal sparing fixation techniques (n = 13; complication rate 30 %) (p = 0.06). Complications included growth arrest, loss of reduction, persistent loss of range of knee motion, malunion and peroneal nerve injury. In their retrospective study of 55 displaced fractures requiring reduction, Garret [15] et al. reviewed 44 cases treated with surgical fixation. The majority of these (40/44) were treated with two percutaneous smooth K-wires or Steinman pins (1.8–3.2 mm diameter) crossing the physis. The remaining four cases were treated with physeal sparing screws. They reported a 21.8 % overall prevalence of physeal arrest. Fractures treated with K-wires or pins that crossed the physeal plate were associated with a 17.5 % rate of growth arrest, compared to injuries treated in cast alone (27.3 %) and with screw fixation (50 %) (p = 0.2). The small number of cases in the different treatment arms prevent the demonstration of a statistically significant (p < 0.05) difference. However, the results tend to favour the argument that smooth wires or pins violating the physeal plate do not contribute to growth arrest.


What Other Factors Increase the Risk of Growth Arrest?


In the meta analysis by Basener et al. [14], the prevalence of growth disturbance was least in SH I injuries (36 %) and most in SH IV (64 %), followed by SH II (58 %) and then SH III (49 %) injuries. This is consistent with other studies that suggest increasing SH classification increases the rate of growth arrest [4, 5]. The reported increased rates of growth arrest seen in SH II injuries may be due to the large number of these cases in all studies, causing a skewing of the data. It may also be related to the fact that although injuries in the lower SH classifications (SH I & II injuries) have growth arrest, it is not as clinically significant as in the higher classifications (SH III and greater injuries). This would concur with the findings of Czitrom et al. [4]who reported that 20 of 29 SH I or II injuries had some degree of shortening but only 3 of 29 had an LLD greater than 1.5 cm.

Riseborough et al. [16] reported a rate of 57 % and 26 % for LLD and angular plane deformity respectively in their study of 66 fractures. When comparing age groups, they found 19 of 23 cases (83 %) within the juvenile age group (2–10 years old) had an LLD or angular plane deformity compared with only 18 of 36 (50 %) in the adolescent group (11 years and older). They postulated that as most juvenile injuries were associated with high energy trauma, they would lead to more significant growth sequale compared with the low energy sports injuries sustained by adolescents. Eid and Hafez [3] found similar trends in their study, with both shortening and a LLD most common in the age group 2–11 years [shortening 28 of 49 (57 %); angular plane deformity 33 of 49 (67 %)]. Garrett et al. [15] further confirmed the positive association between physeal bars and higher energy injuries (11 of 12 compared with 1 of 19 in low energy injuries) and an increasing SH classification (100 % SH IV, 50 % SH III and 17 % SH II injuries).



Anterior Tibial Spine Fractures


Fractures of the anterior tibial spine are an uncommon injury amongst the paediatric population, and were first reported in children by Pringle in 1907 [17]. They are reported to be the cause of acute knee haemarthrosis in 5 % of cases [18], and occur most commonly from hyperextension or hyperflexion injuries when skiing, falling from bicycles [19], during field sports [20] and road traffic accidents. They are most common in the 8–14 years age group [19, 21], with a peak incidence between 11 and 13 years [22, 23]. Meyers and McKeever [19] originally classified these injuries into three types: Type I is an undisplaced injury; Type II is a displaced injury with an intact posterior cortex and Type III injuries are completely detached from the tibial plateau. They also described a Type III+ which represents a completely displaced and rotated fragment. Zaricznjy [24] later added a type IV injury which is a multifragmentory spine fracture. Historically, they were often referred to as the adolescent anterior cruciate ligament (ACL) injury and were thought to occur due to incomplete ossification of the tibial spine, requiring less tensile force to cause injury than the ACL [25]. Although a large proportion of the studies on this subject are retrospective, more recent comparative prospective studies have been published looking at specific aspects of management of this condition.


Should Type II Fractures Be Treated Operatively or None Operatively?


Over the years, there has been much debate about the optimum treatment of the type II injury. In Meyers and McKeever’s [19] original description of 35 paediatric patients, type II injuries (n = 17) were treated with aspiration of haemarthrosis and cast immobilisation. Open reduction and internal fixation (ORIF) was reserved for type III injuries only (n = 8). Sixteen of the seventeen type II injuries had an excellent outcome, with the remaining one reporting a good outcome. Interestingly, only five of the eight type III injuries were reported to have an excellent outcome at average follow up of 3 years (range 0.5–20 years). These findings were confirmed by a follow up report just over a decade later by the same authors [26], when they once again demonstrated an excellent outcome with type II injuries treated with cast immobilisation (23 out of 24), and lead them to conclude that all type II injuries can be treated with closed reduction and casting. Despite this long understanding, none operative management has theoretically been associated with non anatomical reduction causing non or malunion, ACL instability and loss of knee range of motion.

Baxter and Wiley [23] reported on 13 type II injuries from a total of 42 patients in their study. Five of these were treated with cast immobilisation, and at follow up (between 3 and 10 years), there was no clinical difference in ACL laxity between the injured and the normal knee. Seven type II injuries were treated with closed reduction and one with open reduction. In both treatment modalities there was a mean difference in anterior translation of the tibia on the femur of 3.5 mm, but this was not associated with clinical instability. Eight of the thirteen (62 %) patients with type II injuries had more than 10° loss of extension, but interestingly the prevalence was greater in type III injuries (81 %), even in those that had an open reduction (52 %) or a closed reduction (41 %). Edmonds et al. [27] compared ORIF, arthroscopic reduction and internal fixation (ARIF) and closed reduction and casting in displaced type II and III injuries. They found 16.7 % of fractures that were treated with closed reduction and casting required subsequent operation for loose bodies, instability and impingement. This subset of patients that required surgery after an initial period of none operative management had a mean displacement of 6.7 mm, which led Edmonds et al. [27] to conclude that displacement of less than 5 mm may be a safe cut-off for non-operative management and a greater displacement is an indication for surgical reduction and fixation. Unfortunately, the small number of subjects involved in this subgroups analysis makes it difficult to extrapolate these results, and there is no indication from Edmonds et al. of how many of these injuries were type II and how many were not.

Another argument for surgical treatment of type II injuries is to remove any soft tissue interposition which could prevent complete fracture reduction. Falstie-Jensen and Søndergård Peterson [28] reported on four cases of meniscal incarceration, which required arthroscopic reduction, three of the four occurring in type II injuries. Other studies have reported rates of soft tissue interposition of between 32 % and 100 % [27, 29] in these injuries. Tudisco et al. [22] argue that accurate initial reduction is the key to a good prognosis, and advocate all type II injuries be treated with surgical reduction and fixation. In their study of 14 patients with mean follow up of 29 years (range 12–42), 3 (21 %) had type II injuries. Two were treated with cast immobilisation alone, and one was treated with ARIF. Post operative care included immediate weight bearing and continual passive motion for 6–10 hrs a day for the first 3 weeks. At follow up all had a full range of motion, but the two treated with cast immobilisation did have signs of clinical instability as demonstrated by the KT-1000 arthrometer. The small numbers in this study preclude any valid conclusions. Gans et al. [30] reported a total of ten non unions in 580 patients, 80 % of which occurred in type II (n = 2) and type III (n = 6) injuries that were treated non-operatively. Although small, the risk of non union seems to be more common in type II injuries treated non operatively than with surgery, and this might support the argument for operative fixation. In addition, they reported a prevalence of knee laxity of 22.2 % as demonstrated by positive anterior draw and Lachman tests, and 7.8 % as demonstrated by positive pivot shift test in subjects that had sustained type I or II injuries. This suggests that a proportion of type II injuries can have residual laxity which might be prevented by surgical fixation. This would need to be explored further through the use of controlled trials. What is not in doubt is the significant difference in these measures of laxity that are seen in type III and type IV injuries. Gans et al. [30] reported these rates to be between 40 % and 60 %.


Is There a Difference in Outcome Between Arthroscopic and Open Surgery?


The study by McLennan [31] was one of the first published on the use of arthroscopy in the treatment of these injuries. He reported on 35 type III injuries, and used arthroscopy to reduce the fracture fragments which were then held with either cast immobilisation or percutaneous K-wires. Patients with isolated tibial spine fractures treated this way were able to return to pre injury function between 3 and 4 months after surgery. McLennan claimed that arthroscopic assisted reduction helped to reduce hospital stay and rehabilitation time, but his study had no control group to compare with. Since then, other authors have gone on to show that arthroscopic surgery for type II-IV injuries can achieve good outcomes including functional knee scores, range of motion and low rates of non union [32].

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Apr 7, 2017 | Posted by in ORTHOPEDIC | Comments Off on Evidence-Based Treatments for Fractures Around the Knee Joint

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