The very interesting topic of alkaptonuria including metabolism of proteins and particularly of aromatic amino acids has been reviewed in this book on the basis of largely the authors’ own novel observations. The fact that the whole work is based on entirely original, own material conveys so much new information and simultaneously points out so many issues that the book deserves to be published in every world language because such a publication would become the source of many papers for authors worldwide. There is nothing to criticise in any part of the book even if the most stringent review is applied, and I can only heartily recommend it. I believe no other publication in Slovak scientific literature has the same standard from the point of view of international and world significance as the work of Siťaj, Červeňanský and Urbánek. Therefore, it deserves the best standards of publication possible.