Fig. 27.1
Tonometry measurement (illustration of the tonometer in use)
Two independent assessors measured all patients using the agreed standardised protocol. Nodules to be assessed were identified and agreed by both assessors for each DD patient, marked on the hand and recorded on a diagram on the reporting sheet. Measurements for all healthy volunteers were taken at 3 predefined and marked palmar and digital locations according to the protocol. Each assessor was blinded to the score recorded by the other. Measurements were taken during the same session by each assessor in turn for all participants. Three measurements were recorded for each participant at the selected site on the palm or digit. Statistical analysis was performed using the PRISM statistical software programme. Inter-observer was calculated using Pearson’s correlation coefficient (95 % CI). Normal distributions of data were confirmed using the D’Agostino and Pearson omnibus normality test. Data for patients with DD and healthy volunteers were compared using an unpaired t-test.
27.3 Results
Thirty-seven participants were recruited to the study: 25 patients with Dupuytren Disease and 12 healthy volunteers. The ages of the healthy volunteer (mean ± SEM, 61.4 ± 3.1 years) and the patients with Dupuytren Disease (64.5 ± 2.1) were similar, as was the ratio of male to female patients in both groups (3:1). The demographics are summarised in Table 27.1.
Table 27.1
Table showing numbers of study patients and healthy volunteers with age ranges
Participants | Patients | Patients mean age (range) | Healthy volunteers | Healthy volunteers mean age (range) |
|---|---|---|---|---|
Male | 19 | 64.9 (43–82) | 9 | 60.2 (49–79) |
Female | 6 | 63.2 (54–70) | 3 | 65 (51–72) |
Total | 25 | 64.5 (43–82) | 12 | 61.4 (49–79) |
We found that the tonometer readings for the Dupuytren patients were higher compared to the matched healthy volunteers (Table 27.2).
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Table 27.2
Table showing results of tonometry readings and extension deficit for patients and healthy volunteers
Dupuytren Disease, affected hands only (mean ± SEM) n = 25 | Healthy volunteers, both hands (mean ± SEM) n = 12 | p value | |
|---|---|---|---|
Tonometry | Mean 53 ± 8 | Mean 32 ± 3 | <0.0001 |
Extension deficit (MCPJ + PIPJ) | 11° ± 20° | 1° ± 2° | 0.0018 |
Related posts:
Efficacy of Using Local Anesthesia Before Collagenase Injection in Reducing Overall Pain Experience in Patients Treated for Dupuytren Contracture: A Quasi-Randomized Study
Introduction to Radiation Biology When Treating Hyperproliferative Benign Diseases
Controversy: How to Treat Severe PIP Contractures? – Surgical Correction
Favorite Options of German Hand Surgeons in the Treatment of Dupuytren Disease
Effect of Delayed Finger Extension on the Efficacy and Safety of Collagenase Clostridium Histolyticum Treatment for Dupuytren Contracture
Controversy: The Contracture in Dupuytren Disease Is a Passive Process
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