International evidence-based guidelines recommend a multitude of nonsurgical treatment options for the management of osteoarthritis. This article summarizes the evidence available for patient characteristics that have been analyzed as potential predictors of response to nonsurgical interventions for patients with hip and knee osteoarthritis. The specific variables targeted for this review include body mass index, psychological factors, muscle strength, tibiofemoral alignment, radiographic changes, and signs of inflammation. Several studies provide moderate to good evidence of potential predictors of response to nonsurgical treatments, and areas for future research are illuminated.
Key points
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Numerous studies have explored patient characteristics, including body mass index, psychological factors, muscle strength, tibiofemoral alignment, radiographic changes, and signs of inflammation, as potential predictors of response to nonsurgical interventions for the management of osteoarthritis (OA) of the hip and knee.
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Often the sample sizes used by these studies have been inadequate in yielding sufficient numbers of responders to the interventions to allow for analysis of the potential predictors identified.
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Several well-designed studies have been adequately powered to provide some evidence for clinical characteristics that do or do not predict response to nonsurgical interventions for participants with hip and knee OA.
Related posts:
Epidemiology of Osteoarthritis
The Measurement of Joint Mechanics and Their Role in Osteoarthritis Genesis and Progression
Diagnosis and Clinical Presentation of Osteoarthritis
Surgery for Osteoarthritis of the Knee
Update on the Role of Muscle in the Genesis and Management of Knee Osteoarthritis
Nonarthroplasty Hip Surgery for Early Osteoarthritis
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